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Attitudes of medical students toward mental retardation: a prelmininary study. Co-expression of Fos immunoreactivity in protein kinase (PKC gamma)-positive neurones: quantitative analysis of a brain region involved in learning. The New Zealand cataract and refractive surgery survey 1997/1998. Our results demonstrate changes in DNA methylation occur in female rats from prepuberty to puberty suggestng DNA methylation may play a crucial role in the regulation of puberty onset.

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The primary treatment consisted of surgery and whole-abdomen radiation followed by adjuvant alkylating agent chemotherapy. Erratum: Extraction of the multifragmentation time scale in intermediate energy heavy-ion reactions Contrasting authentic versus play-acted stimuli during uncued trials indicated that play-acted stimuli spontaneously up-regulate activity in the auditory cortex and regions associated with emotional speech processing.

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Enhanced mineralization of atrazine in compost-amended soil in laboratory studies. Mur ligases play an essential role in the intracellular biosynthesis of bacterial peptidoglycan, the main component of the bacterial cell wall, and represent attractive targets for the design of novel antibacterials. In this paper we present the case and a review of the relevant literature. When driving a car, he suddenly developed severe headache and this was followed by nausea and vomiting. The ideal laboratory model should have the ability to (a) clearly detect evidence of neuronal injury and recovery, (b) accurately measure morphologically the extent of these changes, and (c) provide functional evidence for damage and recovery.

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Immunocytochemistry identified the migrating cells mainly as fibroblasts with some intermingled epithelial cells. Surprisingly, while deletion of E delta severely impaired germline TCR delta expression in double-negative thymocytes, absence of E delta did not affect expression of mature delta transcripts in gammadelta T cells. Our study goal was to estimate the effectiveness of fish consumption advisories in reducing exposure of infants and children to POPs. We included 33 patients with established CHD or CHD risk factors, whose serum cholesterol did not achieve NCEP target level. The histology revealed an acantholytic epidermis and focal parakeratosis.

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Machado-Joseph disease (MJD) is the most frequent dominantly inherited spinocerebellar ataxia. The widespread use of pharmaceuticals in both human and animal populations, and the resultant contamination of surface waters from the outflow of water treatment facilities is an issue of growing concern.

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RAD-51 localization requires the recombination genes spo-11 and mre-11 as well as chk-2, which is necessary for homology recognition and presynaptic alignment. T cells are necessary for viral clearance, and many age-dependent intrinsic T cell defects have been documented. However, the precise mechanism of growth promoting activity of HBZ is poorly understood.

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A biologically based pharmacodynamic (BBPD) model was developed in order to describe and simulate chemically induced lipid peroxidation in precision cut mouse liver slices. It is unknown whether these infants will continue to snore through childhood and, if so, whether the associated neurocognitive deficits will become worse with time. This paper focused on the pathogenesis, surgical treatment and terminology of this anomaly. Chronic recurrent pancreatitis due to aneurysm of splenic artery

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Of maize and men: reproductive control and the threat to genetic diversity. A 74-year-old woman received chemotherapy and a total of 60 Gy of radiation therapy to the right hilum and mediastinum for small cell carcinoma of the suprahilar area of the right lung. In this review minimum effective and maximum tolerated doses cannot be identified. We and others have shown that phosphatidylinositol 3-kinase (PI3K) is recruited to and activated by E-cadherin engagement. Thus there may be a common receptor which binds TS, malarial proteins, and properdin.

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Regulation of brain-derived neurotrophic factor messenger RNA and protein at the cellular level in pentylenetetrazol-induced epileptic seizures. The objective of our study was to investigate the relationship between hepatic adenoma and liver steatosis. The neck dissection side affected by surgery demonstrated higher levels of upper and middle trapezius muscle activity during exercises involving overhead movement. Some patients, however, present without clinically apparent systemic findings.

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Following 6 months of alcohol consumption degenerated granule cell dendritic profiles were randomly dispersed over the granular layer surrounding mossy fiber terminals. ZNF198-FGFR1 transforms Ba/F3 cells to growth factor independence and results in high level tyrosine phosphorylation of STATS 1 and 5.

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The various techniques available for the dynamic assessment of bladder function, including uroflowmetry, cystometrography, urethral closure pressure profiles, and sphincteric electromyography are presented. The effects of cholesterol feeding on serum and liver cholesterol levels, fecal and biliary bile acid levels, bile acid pool size and bile acid composition were examined in 2-, 12- and 24-month-old male germ-free rats. Overall functional characteristics of the HPA axis in adult organisms are at least partially a result of neonatal experience. Cell density and the percentages of proliferating cell nuclear antigen-positive cells and terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling-positive cells were measured, and a scoring system ranging from 5 points (complete healing) to 0 points (no evidence of healing) was used. In subsequent investigations the authors will submit eventually data from prenatal and postnatal investigations.

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The peak of incidence was observed in the age group 45-64 years. The results suggest that BSER monitoring may be useful in the early detection of brainstem compression following jugular vein ligation in head and neck surgery. This activity of cytosolic factors was saturable, heat-sensitive, and insensitive to N-ethyl-maleimide.

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Contribution to the use of the defense reaction to electrical skin stimulation in the toxicology of substances with central nervous system effect. The treatment of serious habitual sexual delinquents, especially homosexuals, with special reference to castration

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The dermatologist, unfamiliar with handling of neonates in the nursery, should be capable of recognizing and dealing with these phenomena when encountered in the acute stage or with their residue. Bystander cardiopulmonary resuscitation (CPR) has been shown to significantly improve outcome in sudden cardiac arrest in children.

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Epidemiology of clinically diagnosed community-acquired pneumonia in the primary care setting: results from the 1999-2000 respiratory surveillance program. The Caerphilly and Speedwell collaborative heart disease studies. In other words, school counseling can function as a complementary and effective social support for high school students.

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Many wonder whether such care differs from what we have always done and have doubts about cost effectiveness and government motives. Some of them (TIF-2) are up-regulated by androgens, whereas the expression of others increases during androgen ablation (p300, CBP, and Tip60).

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The role of Bach1 in ultraviolet A-mediated human heme oxygenase 1 regulation in human skin fibroblasts. We have cloned the 2.6 kb full-length cDNA for avian UDPG-PPase and confirmed its up-regulation in hypertrophic versus non-hypertrophic cartilage by Northern-blot analysis.

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On the other hand, the loss of the AvaII site d, which in Italy was only found in the above-mentioned association, does not always produce a new BamHI site, as observed in other Caucasian groups. Leishmania infection consists in two sequential events, the host cell colonization followed by the proliferation/dissemination of the parasite.

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Therefore, the energy supplement should be lower than energy consumption during the early stage of burns. Depending on the reaction conditions and substitution at the enyne, their dicobalthexacarbonyl complexes led preferentially to the exocyclic 1,3-diene or to the PK cyclopentenone product.

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In the present study the cytotoxicity and radiation potentiation of three novel analogues of these compounds by replacing 2,4-dinitrophenyl moiety with 2-methyl-5-nitroimidazole, a known radiosensitizer and cytotoxic agent was investigated. Each patient received a validated questionnaire to evaluate knowledge, attitudes and fears regarding IBS.

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Cue cards prompted responses and plastic food models assisted in estimating usual amounts consumed. Resources for planning palliative and end-of-life care for patients with kidney disease.

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Parental protection of extremely low birth weight children at age 8 years. Pulmonary strongyloidiasis presenting as chronic bronchitis leading to interlobular septal fibrosis and cured by treatment. The mRNAs encoding MMP-2, MMP-9 and MT1-MMP were also increased in Alport dogs suggesting that elevated expression of MMPs reflects events in the progression of Alport syndrome in dogs. The present study investigated expression of HDAC8 in GC cell lines and tissues, and the roles of HDAC8 inhibition in the proliferation, cell cycle and apoptosis of gastric cancer cells and explored the potential mechanisms.

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Contractile force is significantly reduced in right atrial skinned human fibers with DD. Cor a 1.04 has been identified as the major hazelnut allergen in 65 European patients with positive double-blind, placebo-controlled food challenge results to hazelnut. This article discusses assessment, diagnosis and management of COPD.

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Alkaliphilic haloarchaea, a distinct physiological group from the closely related neutrophilic haloarchaea, represent an underutilized resource for basic research and industrial applications. We observed that the inhibitory effect is ultimately mediated by soluble factors, the production of which requires SC to be licensed in an inflammatory environment by cell contact.

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Thus, the balanced translation of alpha and beta mRNA is primarily the result of a 4-fold difference in the rate of ribosomal elongation. Integrated Laplacian-based phase unwrapping and background phase removal for quantitative susceptibility mapping. Safrole-DNA adduct in hepatocellular carcinoma associated with betel quid chewing. Congress Summary: The 24th Congress of the International Society for Rotary Blood Pumps.

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The cumulative incidence of NMSC in our cohort of HTR is comparable to published data on HTR adjusted according to the geographic location. Cultured murine cerebral microvascular endothelial cells contain von Willebrand factor-positive Weibel-Palade bodies and support rapid cytokine-induced neutrophil adhesion. Thus, Chk1 is an important factor in the resistance of normal cells, and some transformed cells, to HDACi-induced cell death.

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A highly sensitive peroxidase-antiperoxidase method for detection of H-Y antigen on cultivated human fibroblasts. This is the opposite of the usually described effect of IFN treatment in mice, which is inhibition of tumor development and delayed mortality, as was indeed observed in the C57BL/6 mice in the present experiments.

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A method has been developed for the isolation of highly polymerized DNA on a large scale from calf thymus and herring sperm by the use of pentadecafluorooctanoate. Using both isolated neuronal as well as brain slice approaches, we address mechanisms behind such injury. These reported changes in the secretion and response of both central and peripheral hormones that regulate appetite. However, the exon-intron structures of the tunicate IRK genomes showed considerable similarities to those of Caenorhabditis.

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In this paper we describe a novel, dominant pleiotropic tomato (Lycopersicon esculentum)-ripening mutation, Cnr (colorless nonripening). The present mechanism differs from the flashing ratchet model of the kinesin-microtubule molecular motor. In special cases, activated factor VII (FVIIa) may be used instead of FVIII or FIX.

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Mental imagery and dyslexia: a deficit in processing multipart visual objects? The associations between MTR A2756G and MTRR A66G polymorphisms and NTD risk in children have been investigated in many studies. This focus is necessary to assure that critical care nurses have the expertise to care for patients who need astute surveillance for complicated physical problems and their emotional sequelae, as well as in-depth knowledge and skills related to care coordination for patient stabilization and transfer.

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This report describes the first clinical use of the Ohio Contrast Cards, a new test that measures the maximum spatial contrast sensitivity of low-vision patients who cannot recognize and identify optotypes and for whom the spatial frequency of maximum contrast sensitivity is unknown. The serum levels of growth hormone and somatomedin-C spontaneously normalized seventeen days after this episode and have remained normal for two years. No significant differences were observed in enamel volume and density, rod-interrod organisation, and its attrition. Acclimation of photosynthesis and respiration is asynchronous in response to changes in temperature regardless of plant functional group.

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Fabrication and Characterization of Electronic and Optical Properties of Polyaniline Nanopatterns. The balance between these factors may change with fruit availability and may influence party size in different periods. The value of the recognition of the previously unreported CT findings of visceral leishmaniasis is discussed.

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The human herpesvirus family is composed of large, enveloped DNA viruses that have close structural similarity. Effective use of cloud computing on large biological datasets requires dealing with non-trivial problems of scale and robustness, since performance-limiting factors can change substantially when a dataset grows by a factor of 10,000 or more.

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In this paper we focus on its applications in the field of ophthalmology and retinal imaging. Possible potential mechanisms underlying the transition of highly differentiated Sertoli cells to dedifferentiation, limited by proliferation and reproduction and not accompanied by significant phenotypic changes, are discussed. Effects of acupuncture on declined cerebral blood flow, impaired mitochondrial respiratory function and oxidative stress in multi-infarct dementia rats. Oncolytic engineered herpes simplex viruses (HSVs) possess many biologic and functional attributes that support their use in clinical trials in children with solid tumors.

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We found that subjects were less successful at inhibiting their initial saccades as the inter-target delay increased. Protection by 20-5,14-HEDGE against surgically induced ischemia reperfusion lung injury in rats. To investigate whether FGF, TGF, PDGF, IL-1, and IFNgamma modulate expression of these cytokines in cultured human osteoblast-like cells we used flow cytometry.