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Retinoic acid response element in the human alcohol dehydrogenase gene ADH3: implications for regulation of retinoic acid synthesis. As one or the other tight-junctional appearance was always seen in a single freeze-fracture replica, it is reasonable to assume that the two tight-junctional appearances reflect a sequential pattern of differentiation peculiar to the whole surface of the olfactory epithelium, i.e. Human T-cell leukemia virus type 1 Tax-deregulated autophagy pathway and c-FLIP expression contribute to resistance against death receptor-mediated apoptosis. T-helper cells produce a T-cell replacing Factor (TRF) upon mitogenic or antigenic stimulation. Thus, our observation expands the spectrum of liver malformations found in KS with the inclusion of hepatic fibrosis and supports the evidence that hepatic abnormalities may not be uncommon in KS.

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These results indicate the activation of keratocytes into the fibroblast and myofibroblast wound phenotypes and the potential source of corneal scarring commonly observed in keratoconic corneas. This quantitative, objective and easy to use technique should perhaps be deployed more widely to evaluate its potential in monitoring the effects of sports-related head injuries.

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To determine the feasibility of using ESD for treating large superficial colorectal tumors and to evaluate the clinical outcome. Cognitive trio: relationship with major depression and clinical predictors in Han Chinese women. The delivery of amiodarone to a patient receiving ECMO may be complicated by the administration of large blood volumes, circuit changes, and binding to the circuit. Mixing experiments showed that unfertilized eggs do not contain a dominant inhibitor of replication, nor does fertilization induce the appearance of a soluble, dominant activator.

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Local VEGF expression was correlated significantly with tumor size, advanced stage and lymph node metastasis, but not correlated with peripheral VEGF levels. Distribution of trypsin inhibitors in the sera of various animals.

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Previously, we reported that glucose-deprived astrocytes are more vulnerable to the cytotoxicity of peroxynitrite, the reaction product of nitric oxide and superoxide anion. Overview of toxicological aspects of polybrominated diphenyl ethers: a flame-retardant additive in several consumer products.

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Clinical symptoms do not significantly distinguish bacteremic from nonbacteremic children with UTI. The diagnosis of a pulmonary vein varix with a recently introduced new CT technology, multi-slice helical CT, is discussed. Although this virus could be a new causative agent for nonA-nonG hepatitis, high healthy carrier rate, no relation with hepatocellular carcinoma and no evidence of amplification in parencymal hepatocyte might lead to less importance in liver disease.

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Estimating the relative stability of polymorphs and hydrates from heats of solution and solubility data. Cell cycle distribution analysis showed an arrest of myeloma cells at M/G2 phase by vincristine and Adriamycin and an inhibition of myeloma cells from entering into S phase by dexamethasone. Thus moxonidine is endowed with a specific central site of action, presumably by stimulating central presynaptic alpha 2-adrenoceptors. The objective of this study was to identify and assess implementation strategies that facilitate quality improvements in the respiratory care of extremely low birth weight infants.

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Whereas treatment with NNK alone caused mainly tumors in the respiratory tract of the treated offspring, cotreatment with ethanol (EtOH) and NNK shifted the site of tumor formation to the pancreas. This review summarizes what has been learned from mouse models and highlights the utility of manipulating complex signaling pathways in vivo. She had a car accident and, initially, presented with a normal examination. Stimulus-locked ERPs confirmed that children showed greater stimulus-level interference for repeat trials, especially with bivalent stimuli.

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OLT in patients with familial amyloidotic polyneuropathy (FAP) was first performed in 1990 at the Karolinska Institute in Sweden, and because the results were promising other centers took up the procedure. Motion perception in migraineurs: abnormalities are not related to attention. The number of studied patients was rather small and no control group was studied in parallel.

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We searched six databases and eight major journals supplemented with screening references of eligible studies. Altered activities of antioxidant enzymes in patients with metabolic syndrome. In subjects with parietal lobe lesions, performance on motor and language tasks differed as a function of the side of space to which subjects directed their attention or acted.

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Carbohydrate components in the epithelial mucin of hagfish, Myxine glutinosa. These findings suggest the possibility that VEGF overproduction is associated with development of vasculitis in some cases of DM complicated with peripheral neuropathy. Differential effects of ADH on sodium, chloride, potassium, calcium and magnesium transport in cortical and medullary thick ascending limbs of mouse nephron.

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The use of operational criteria for evaluations of mental competency Esophagogastric devascularization with esophageal transection using a stapler through laparoscopic surgery is a feasible technique that accomplishes the same and all objectives of the open procedure. Bronchial arteriographic evaluation and surgical treatment of pulmonary aspergillosis Many of our training and outreach initiatives have been in collaboration with the Research Centers at Minority Institutions (RCMI), integrating NCIBI and RCMI faculty and students, culminating each year in an annual workshop. Accumulation of artemisinin can be induced by the phytohormone jasmonate (JA).

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Aortic valve: do its nervous and contractile elements have any role? However, recent insights suggest that properties associated with the red blood cell limit NO-Hb interactions under physiological conditions, and provide some resolution to the question of how NO functions in the presence of blood. Respiratory health of workers exposed to swine confinement buildings only or to both swine confinement buildings and dairy barns.

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Existing literature shows that the rates of stress fracture for female athletes and female army recruits are higher than their male counterparts. EHD serotype 1 viral RNA was detected by hybridization in infected flies fixed in ethanol at room temperature for 7 d and in unfixed (frozen) infected flies. Macrophage depletion following liposomal-encapsulated clodronate (LIP-CLOD) injection enhances megakaryocytopoietic and thrombopoietic activities in mice. On micromorphology of the neuromuscular junction of the afibrillar-tonic skeletal muscle fiber in the frog (Rana temporaria L.) The objective of this study was to evaluate the impact of this policy on neonatal outcomes and obstetric practices.

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During embryonic morphogenesis, INX-3 expression becomes more restricted. LDL oxidation by PMN was also not different between the NIDDM and control groups.

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Data from the KIMS study demonstrate that prolonged GH replacement is associated with a reduction in the number of patients requiring assistance with daily living and a significant reduction in sick leave and hospital admissions. Once-every-2-weeks and once-weekly subcutaneous epoetin beta regimens are equivalent in the maintenance phase of anemia treatment in long-term stable hemodialysis patients without diabetes, with similar safety profiles.

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Through these applications we show that the performance of the NNs matched or exceeded the performance of traditional methods. The purpose of this study was to test whether the addition of intensive clinical case management to clinical guidelines could lead to a reduction in LOS that was not achievable by guidelines alone, while maintaining quality of care. The results obtained support the hypothesis that KARs are involved in bi-directional regulation of excitatory synaptic transmission in the spinal cord SG region, and that these actions may be of critical importance for nociception and the clinical treatment of pain. Concise review: The Sox2-Oct4 connection: critical players in a much larger interdependent network integrated at multiple levels.

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We also report on the thermally promoted ripening of these nanoparticles under mild conditions to yield a dispersion of 11.3 nm gold nanoparticles. Multiple climbing fibers signal to molecular layer interneurons exclusively via glutamate spillover. Carrots macerated in a Stomacher Lab Blender also showed an antilisterial activity which resulted in a decrease in number of viable bacteria and in sublethal damage. Effect modification of the association of cumulative exposure and cancer risk by intensity of exposure and time since exposure cessation: a flexible method applied to cigarette smoking and lung cancer in the SYNERGY Study.

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The ability of NPY to potentiate exogenous NE-induced force of contraction was restricted to larger arteries where NPY had little or no contractile effect. citri to describe fungi associated with citrus black rot is not justified and it is proposed that citrus black rot fungi be referred to as A. In this study, a novel family of transposable elements, designated Spring, has been identified in the apple genome.

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The GFR was measured using 51 Cr-EDTA clearance and endogenous Ccr. Renal function during therapy in patients with congestive cardiac failure. Inter-relation between interleukin (IL)-1, IL-6 and body fat regulating circuits of the hypothalamic arcuate nucleus. Correlation with laboratory data and early intervention are vital in achieving a favorable outcome for both mother and fetus.

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Effect on oral pH changes and taste perception in 10-14-year-old children, after calcium fortification of a fruit juice. Higher rates of cardiovascular events reported in primary aldosteronism could be due in part to the increased prevalence of the metabolic syndrome in this disorder.

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Detection of residual and recurrent differentiated thyroid carcinoma by serum thyroglobulin measurement. The HIV-1-positive addicts were compared to the HIV-1-negative addicts with respect to mean age, duration of abuse, residence and cause and manner of death. IL-1beta mRNA was strongly and similarly increased in normoglycemic and hyperglycemic groups on days 1, 3, and 7 after transplantation compared with freshly isolated and cultured islets. Part 1 reviews recently approved drugs with labeled pediatric indications, and Part 2 will review recent drug approvals in adults that have potential use in pediatrics and have active studies.

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Together with UGT(olf), olfactory GST provides the necessary broad coverage of covalent modification capacity, which may be crucial for the acuity of the olfactory process. Incidence rates of self-reported skin abscesses and verified episodes of endocarditis were calculated.

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Colonoscopy is currently regarded as the gold standard for the detection of polyps and cancers in the colon and rectum, and is the preferred method of screening for colorectal cancer in Europe and the USA. To optimize the antiplaque effect of CHX, it seems best that the interval between toothbrushing and rinsing with CHX be more than 30 minutes, cautiously close to 2 hours after brushing. Options for such patients include addition of lamotrigine or a second mood stabilizer, or a newer-generation antidepressant such as a serotonin re-uptake inhibitor or bupropion, or the atypical antipsychotic olanzapine.

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In comparison with the administration of HSV-1716 alone, irradiated PA-1 cells, infected at two multiplicities of infection with HSV-1716 and injected i.p. Sporadic inclusion-body myositis (IBM) is the most common, progressive muscle disease of older individuals.

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Carcinoma associated paraneoplastic peripheral neuropathies in patients with and without anti-onconeural antibodies. Coronary angiography showed absence of significant disease and left ventricular function was found to be unremarkable 1 month after the acute event. Inhibin: definition and nomenclature, including related substances.

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Single use of the contrast agent Optison can be recommended for enhancement of the subcostal Doppler signal in dogs, in which plain Doppler signals are difficult to obtain. When young adults engage in SAM use they report experiencing greater negative physiological and cognitive effects. Recombinant Escherichia coli expressing the membrane-displayed BM95-MSP1a fusion protein were used to test bacterial viability in the baits and the antibody response in orally immunized wild boar. Of the three enzymes, TfdD of Ralstonia eutropha JMP134 (pJP4) was most specific, since its specificity constant for 2,4-dichloro-cis,cis-muconate was the highest, while the constants for cis,cis-muconate, 2-chloro- and 2,5-dichloro-cis,cis-muconate were especially poor.

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Our data might provide a rationale for associating bisphosphonates and radiotherapy for the treatment of bone metastases from breast cancer. Consequently, children with CHD were not at increased total metabolic risk. The antibacterial and antimycotic activities of the new compounds were tested.

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To determine the minimal important difference in PAC-SYM score, and the optimum cut-off value for defining responders. However, stent placement for duodenal obstruction beyond the first part of the duodenum is considered technically difficult and is not routinely performed. Despite the nearly universal finding from observational studies that postmenopausal estrogen therapy reduces the risk of CHD and the multiple plausible mechanisms by which estrogen might reduce the risk of CHD, hormone therapy had no benefit in the only large randomized clinical trial to date.

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Femoral neck fractures in older patients: indication for osteosynthesis. MERTK-associated retinal degenerations are thought to have defects in phagocytosis of shed outer segment membranes by the retinal pigment epithelium (RPE), as do the rodent models of these diseases.

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A computerized tomography (CT) scan showed multiple intracranial and intraorbital enhancing masses. Four additional rpoA mutations that affect anaerobic pepT expression have been isolated after localized mutagenesis of the rpoA region. Muon-induced neutron and pion production in an organic liquid scintillator at a shallow depth.

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On the other hand, blood samples were collected from the immunized mice to check the functions of liver and kidney. However, little is known about the interaction between peptides of (prepro)insulin and MHC class II molecules permissive and protective for Type 1 diabetes. Both ICAM-1-targeted agents bound effectively to activated cerebrovascular cells in vitro, generating significant MRI contrast-enhancing effects.

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Our findings suggested that a novel cluster of Chilean sequences emerged resulting from intergenotypic recombination between PCV2a and PCV2d. It measures transcutaneous cerebral tissue oxygen saturation (rSO2). The horizontal 10cm VAS and the Italian version of the MPQ were administered. Hence, the series-level attributes are normalized, and the amount of header data repetition is reduced.

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Examination of lymphocytes and sera from patients with rheumatoid arthritis for evidence of retrovirus infection. Immune activation resulting from NKG2D/ligand interaction promotes atherosclerosis. After reperfusion of the graft, the blood glucose concentration rapidly increased, and regular glucose was administered throughout the operation. We analyzed the quantity of fatty acids in different stones from Chinese and Japanese cases and discussed the role and mechanism of fatty acids in the formation of pigment stones. The status of consciousness and emotions in individuals just before and after decapitation was discussed.

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Traditional remedies used in South Africa for the treatment of gynaecological problems are compared to those used elsewhere in the world. The use of chemotherapy after recurrence in these cohorts was either none, sporadic or widespread. The Skinner Lecture: a cost-benefit analysis of postoperative radiotherapy in the treatment of early breast cancer.

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Treatment of THP-1 cells with PMA led to a 2-fold increase in specific binding of dexamethasone and a 4-fold increase in glucocorticoid receptor mRNA within 12 h. Generalizations of the Glauber model in different directions, using generalized rates, generalized numbers of states at each site, and generalized numbers of interacting sites, are also investigated.

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The identification of T-cell epitopes can be crucial for vaccine development. Split tibialis posterior transfer for equinovarus deformity in cerebral palsy. Streptococcus pneumoniae and Streptococcus pyogenes resistant to macrolides but sensitive to clindamycin: a common resistance pattern mediated by an efflux system.

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Based on the observed and anticipated impacts, adaptation strategies and research needs are discussed. The latter is referred to as motor unit common drive and can be quantified by the common drive coefficient, which is the correlation coefficient between the smoothed firing rates of the two MUs.

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Previous research on eusocial insects shows that experience-dependent changes in brain anatomy (i.e., enlarged MB calyces) are positively correlated with task performance and social interactions. The apoptotic intermediates through which curcumin exhibits its cytotoxic effects against tumor cells are not known, and the participation of antiapoptotic proteins Bcl-2 or Bcl-xl in the curcumin-induced apoptosis pathway is not established.

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Since the suppressive effects of Nal and Oxl on transformation were time-related, they may be due to epigenetic changes. A loss heterozygosity in the region of the TSC2 gene in renal angiomyolipomas has been demonstrated in association with pulmonary lymphangioleiomyomatosis.