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A wealth of observational studies show that low testosterone is associated with insulin resistance and with an increased risk of diabetes and the metabolic syndrome. Organophosphate-induced neurobehavioral effects result in depression. Although musculoskeletal involvement is quite common in SSc (arthritic in particular), there have been few trials and even fewer controlled trials of therapeutic agents in arthritis in SSc. Glioma stem cells are more aggressive in recurrent tumors with malignant progression than in the primary tumor, and both can be maintained long-term in vitro. Annals for Hospitalists Inpatient Notes - Gender Equality in Hospital Medicine-Are We There Yet?

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Results show that the CA1 responses evoked by the optimal stimulations accurately replicate the CA1 responses recorded in the hippocampal slice with intact trisynaptic pathway. In some patients with cerebral ischemia, the test was repeated 4 and 15 days after the acute event, but the follow-up data did not differ from baseline values. The treatment of cervicofacial lymphangiomas has been changing in recent years.

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Finally, the involvement of microRNAs in the promotion and suppression of breast cancer metastasis is reviewed. For accurate determination of HIV-1 RNA copy numbers of each member of Panel 2, they were analyzed using various testing platforms/technologies available through the cooperation of five independent laboratories participating in the study. A random sample of children who were patients in the paediatric clinic over a period of six months (1 June to 31 December 1993) were anthropometrically measured and blood samples taken to determine prevalence of anaemia. The incidence of tuberculosis is rising again in the Western world, due to the emergence of new groups of patients at risk. MUC1 also is a tumor marker and has been implicated in the protection of cancer cells from immune cell attack as well as in cell signaling in some tumors.

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8 In conclusion, aspirin suppresses the proliferation of metastatic B16 cells in a JNK-dependent mechanism. Sixty minutes of daily mobilization and tactile stimulation to the paretic arm and hand for 6 weeks in addition to the usual rehabilitation program. Here, we present a series of experimental results that compares all three implementations, and draw conclusions about the relation between a broad range of reservoir parameters and network dynamics, memory, node complexity and performance on a variety of benchmark tests with different characteristics.

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Previous attempts at applying ultrasound to the field of neurosurgery are reviewed. A survey distributed to the members of the British Association of Stroke Physicians (BASP). Safety and tolerability were analysed using descriptive statistics.

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Analysis of case series have not identified risk factors for hyperglycemia or diabetic ketoacidosis within this population. In addition, as production levels continue to increase, there is an escalating focus on the detoxification of the resulting waste streams to minimize their environmental impact. Moreover, several signaling pathways have previously been defined with lentiginosis except JAK-STAT pathway. Our patient made a good recovery which brings into question the value of negative 20 somatosensory evoked potentials in prognostication with concomitant neck injuries and swelling. Erratum: Lattice dynamics of skutterudites: First-principles and model calculations for CoSb3

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For optimal adjuvant effects lactobacilli had to be injected in a dose of 10(8) into the same site as the antigen. Since the affinity constant for estradiol of antiestradiol antibodies is about 10(8) M-1 while those for breast estrogen-receptor complexes are about 10(9) to 10(10) M-1, it is possible to remove the free steroid from a reaction mixture containing tissue cytosol, radio-labelled estradiol, and the antiestradiol bacterial adsorbent by pelleting the bacteria at low-speed centrifugation. Therefore, sex differences in the expression of these genes are likely to underlie many sex differences in the expression of diseases affected by these genes. They, moreover, appraise the actuarial global survival with no disease (NED) of this group of patients as compared with the survival of women in more advanced age.

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Receptor/transporter-independent targeting of functional peptides across the plasma membrane. Nuclear translocation of IFN-gamma is an intrinsic requirement for its biologic activity and can be driven by a heterologous nuclear localization sequence. Epidemiology and control of nosocomial infections in adult intensive care units.

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Acquired Multidrug Antifungal Resistance in Candida lusitaniae during Therapy. A Nuffield Health Ladder of Interventions approach is proposed as a way to frame the debate surrounding both current compensation mechanisms and how it is expected to change behaviour. In conclusion, interphase cytogenetics represent a non-invasive, sensitive and specific assay for the direct visualization of circulating tumor cells in the peripheral blood. One session was done in 20 patients and two sessions in 2 patients.

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Polymorphisms in the glucokinase-associated, dual-specificity phosphatase 12 (DUSP12) gene under chromosome 1q21 linkage peak are associated with type 2 diabetes. Patients completed a questionnaire that included 1) identification of the person who detected the lesion, 2) the anatomic location of the lesion, and 3) family history of melanoma.

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To evaluate the efficacy and the side effects of paclitaxel (Tesu) in breast cancer patients. Cell and tissue reactions to mineral trioxide aggregate and Portland cement.

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These results indicate that long-term weed control using herbicides reduces soil fertility through reducing organic C inputs, nutrient retention and soil microbes. Use of self-assembled monolayers of different wettabilities to study surface selection and primary adhesion processes of green algal (Enteromorpha) zoospores. The structures of the sesquiterpenes new compounds were established by spectroscopic methods.

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Treponema pallidum hemagglutination assay (TPHA) was the confirmation test for the diagnosis of syphilis in patients who had positive results in the screening test. Tranylcypromine treatment leads to an up-regulation of GABA(B)-receptors and modulates the phospholipid metabolism, which is essential for normal brain function.

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Re: Attitudes and opinions regarding asbestos and cancer, 1934-1965. Effective prophylaxis of acute GVHD should bring about improved patient survival by decreasing severe infections during the first 3 months after transplantation and reducing the incidence of chronic GVHD while not compromising the quality of hematopoietic engraftment or increasing the incidence of leukemic relapse by impairing the graft-versus-leukemia effect.

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To investigate the step at which infectivity was selectively reduced, we compared early events in the life cycles of Hx10 and SF2 viruses using PCR entry and gp120-binding assays. Imaging of ARD affords a fascinating conjunction between the microscopic movement of water, the properties of myelinated white matter fibres, gross anatomy of the brain, and changes of the diffusion of water in disease. In the area of adjustment and mood, however, improvement with gabapentin administration was noted on several variables pertaining to emotional and interpersonal adjustment. Investigating Functional Regeneration in Organotypic Spinal Cord Co-cultures Grown on Multi-electrode Arrays.

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The central ray forms 20 degrees and a 50 degrees angle with the camperian plane on the radiograph. In our screening of micro-organisms for novel bioactive natural products, a new staurosporinone, N-carboxamido-staurosporine (1c), and a new sesquiterpene, (5S,8S,9R, 10S)-selina-4(14),7(11)-diene-8,9-diol (2a), were isolated from the culture broth of the marine-derived Streptomyces sp. Urinary N-acetyl-beta-D-glucosaminidase and incipient diabetic nephropathy

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At least five dystrophin-related proteins are encoded by the Duchenne muscular dystrophy locus. We furthermore found that these molecules are relevant biomarkers for bronchial asthma and atopic dermatitis. Past research emphasizes physical characteristics and medical complications. Epidemiological studies show that rates have increased dramatically in recent y, especially in human immunodeficiency virus (HIV)-seropositive patients. A year later he was again given radiation because of a local recurrence and additionally treated by chemotherapy according to the MOPP scheme.

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Therefore, an inexact multistage fuzzy-stochastic programming (IMFSP) was developed for regional electric power system management constrained by environmental quality. In the Northern Region of Nigeria the behaviour of the local vectors was studied by means of experimental huts fitted with exit window-traps. The orientation maps are obtained using a step-by-step beam scan on a computer-controlled TEM equipped with a CCD camera.

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This review attempts to survey in a uniform manner the available evidence concerning the generation and behaviour of several well-investigated cellular oscillators. Escherichia coli cells transformed with the ileS2 gene exerted pseudomonic acid resistance more than did those transformed with ileS1. Chaperonin containing TCP1 subunit 5 is a tumor associated antigen of non-small cell lung cancer. Energy balance is achieved by means of a concomitant control of both food intake and energy expenditure.

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A clinical study monitoring low-intensity anticoagulant therapy with a standard-sensitivity thromboplastin. It was found that the alloreactive response of D10.G4.1 cells was abolished if the APC were treated with brefeldin A or inhibitors of protein biosynthesis. The formation and secretion of cholesteryl esters in rat hepatocytes are reduced by lovastatin and simvastatin. The tribe Antilopini is monophyletic with Antidorcas marsupialis and Litocranius walleri basal to the large genus Gazella.

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It also discusses novel cancer diagnostic tools and standard and potential treatment options. This is apparently the first animal model of PO neuropathy to be verified histologically. Neurotrophins are important regulators of the development and maintenance of the vertebrate nervous system.

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In these behavioral traits the effect of shared twin environment may depend on zygosity and play a major role in explaining familial aggregation in twin family data. In some cases, computed tomographic scanning and biopsy are required. Examinations of specimens received from Egypt (U.A.R.), November 1965 and 1966 Synergistic activation of the human Btk promoter by transcription factors Sp1/3 and PU.1. The concentrations of both mononitrates were lower on the exercise day, but the difference was already present before the exercise started.

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Previous studies reported that infection with ICP0-null HSV-1 mutants fails to reactivate quiescent HSV, even when the mutant itself undergoes productive replication, leading to the hypothesis that quiescent genomes exist in a silent configuration in which they are shielded from trans-acting factors. Developing a comprehensive system that has a DAP meter in place of a mirror in the collimator would be effective for measuring, recording the dose and maintaining the quality of the DAP meter. MRI is a valuable method for evaluating and assessing anterior ligament reconstructions.

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Mechanism of hemagglutination by adenovirus types 1,2,4,5 and 6. Here, an exoribonuclease, PNPase, was identified in a complex with TCL1. Following the blocking of periodontal input by the injection of local anesthetic around the stimulated tooth, inhibitory responses were abolished.

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Porcine kallikrein-4 activation, glycosylation, activity, and expression in prokaryotic and eukaryotic hosts. The deduced polypeptide had properties typical of outer membrane proteins, with an N-terminal signal sequence and a predicted preponderance of beta structure. Thus, most doctors have learned to perform a lumbar puncture without studying the theory of the procedure in any detail. To estimate the prevalence of opiate use among the subscribers of a large private insurance plan, Empire Blue Cross and Blue Shield (EBCBS).

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Effect of curing-injury Cataplasma on expression of AQP-3 in skeletal muscle of rat model with acute injury in soft tissues DNA flow cytometric analysis of serous ovarian tumors of low malignant potential. Combination therapies with immunosuppressive drugs that exhibit different modes of action improve graft survival, widen therapeutic windows, and reduce the risk of toxic side effects. The permeate quality was found to improve as the cake became more dense with filtration time. The mean PI uptake and the LDH efflux into the medium correlate well for both types of cultures.

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In 33 patients, epicardial bipolar electrograms were intraoperatively recorded from 250 sites during AF. Update: influenza activity--United States and worldwide, 1998-99 season, and composition of the 1999-2000 influenza vaccine.

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Is the abuse of cannabis related to psychopathology, HIV/HCV risk-taking and infectious diseases? Fluorescent in situ hybridization assessment of chromosome 7 copy number in uncultured lung and kidney cells. In contrast, computerized tomography (CT) demonstrated 103 lesions in 90 patients. To examine the effect of extragonadal tumor site on the risk for cardiovascular, hematopoietic malignancies, and solid cancer-related causes of death.

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American Pediatric Society Presidential Address 2000: reflections on the 20th and 21st centuries. Numerous human intervention studies are underway to test this hypothesis. Polymorphisms were characterized by pyrosequencing in 26 patients with ductal histotype breast cancer in a neoadjuvant setting and genotype association with pCR was analyzed.

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Clinicians must work with adolescents to improve their understanding of the potential negative outcomes associated with noncompliance to improve appointment-keeping behavior. These findings are in agreement with the hypothesis that the absence of liver damage in HBsAg healthy chronic carriers is related to immune tolerance to the antigen.

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Neurotrophins are a family of closely related proteins that were identified initially as survival factors for sensory and sympathetic neurons, and have since been shown to control many aspects of survival, development and function of neurons in both the peripheral and the central nervous systems. Clinicians should include malignancy in the differential diagnosis of periprosthetic fluid collections and periprosthetic masses. Effect of antibiotics and their associations on the activity of antitoxic immunity in diphtherial toxin immunization These results indicate that PKCs, but probably not alpha-PKC in particular, are important in these responses.

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Following careful examination, a ventricular aneurysm resection and coronary artery bypass graft were carried out. The solution of the IK problem leads robots to the precise position and orientation of their end-effector. Pregnancy-induced hypertension and infant mortality in triplets. Exposure of monkey kidney epithelial cells (BSC-1 line) to medium with a reduced K concentration (3.2 mM) stimulated growth and transiently activated glyceraldehyde-3-phosphate dehydrogenase (G3PD).

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Sample size formulae for intervention studies with the cluster as unit of randomization. Although the positive benefits of statin therapy are well recognized, the concerns of potential hepatotoxicity with statin therapy have limited use not only in the general population but also in patients with a history of chronic liver disease. WS1279, a novel lipopeptide isolated from Streptomyces willmorei.

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These data suggest that CMC-HA combinations have properties that may be used to formulate artificial tears that optimize ocular retention (through higher low-shear viscosity), while minimizing blur and stickiness during blinking (through lower high-shear viscosity). Screening for anxiety and depression in kidney transplant recipients is essential. coli O9 LPS in the same strain, it was suggested that the rfaL product of S.

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2-substituted quinoline alkaloids as potential antileishmanial drugs. Cumulative application of endothelin-1 (human) markedly constricted goat isolated cerebral arteries in a concentration-dependent manner.

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To determine the relevance of O-6-methylguanine-DNA methyltransferase (MGMT), human mutS homolog 2 (hMSH2), and human mutL homolog 1 (hMLH1) in TP53 mutations in esophageal squamous cell carcinoma, we employed methylation-sensitive high-resolution melting technology and methylation-specific polymerase chain reaction (PCR) to analyze promoter hypermethylation of MGMT, hMSH2, and hMLH1, respectively, in 51 paired tumors and their adjacent normal tissues. This study has shown that preadmission health-related quality of life of our medical, noncoronary patients was substantially reduced compared with a matched general population. Oxygenation of Organoboronic Acids by a Nonheme Iron(II) Complex: Mimicking Boronic Acid Monooxygenase Activity.