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These hypotheses were tested using three different model structures. Bone mineral density and osteonecrosis in survivors of childhood allogeneic bone marrow transplantation.

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We compared expression of HSP70i in skin samples, evaluated the viability of primary vitiligo and control melanocytes exposed to bleaching phenols, and measured secreted HSP70i. Reoperations in cervical total disc replacement compared with anterior cervical fusion: results compiled from multiple prospective food and drug administration investigational device exemption trials conducted at a single site.

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Shape-Controlled Synthesis of Au-Polypyrrole Composites Using Poly(4-vinylpyridine) Brush Grafted on Graphene Oxide as a Reaction Chamber. Ribosomes translate the codon sequence of an mRNA into the amino acid sequence of the corresponding protein. Characterization of a post-translational modification of Campylobacter flagellin: identification of a sero-specific glycosyl moiety.

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At a subcellular level, NPC1 localized to vesicles with the morphological characteristics of lysosomes and to sites near the plasma membrane. PecE/PecF could catalyse the reconstitution of phycocyanobilin(PCB) with apoproteins of alpha-PEC from two different subspecies of Mastigocladus laminosus, as well the site-directed mutated apoprotein of alpha-PEC with Trp at 128 to Phe in vitro, but could not catalyse the reconstitution of PCB with apoprotein of phycocyanin alpha-subunit(alpha-CPC) from Mastigocladus laminosus. 3H-Labeled precursors of glycophospholipid such as ethanolamine and stearic acid were incorporated into CEA produced by both normal and cancerous tissues, suggesting that CEA in normal mucosa is anchored to the cell membrane through a glycophospholipid as in cancerous tissues.

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This report discusses the role the school nurse plays in determining which children are at risk, what needs to be done, and how Medic Alert can provide the needed protection. Interscanner variation in brain MR lesion load measurements in multiple sclerosis using conventional spin-echo, rapid relaxation-enhanced, and fast-FLAIR sequences. Here, we argue that these studies support the subunit transport theory. Effects of the organic layer of hashish smoke extract and preliminary results of its chemical analysis. Accumulation of extracellular matrix (ECM) in the glomerular mesangium is a common feature of many progressive renal diseases.

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Long term effect of diethylcarbamazine medicated common salt on bancroftian filariasis. To document the diagnosis of occupational asthma in a respiratory technologist, the following tests were performed: preshift and postshift spirometry, serial measurements of peak expiratory flow rate and nonspecific bronchial hyperresponsiveness, and workplace challenge test. Traumatic spine injuries (TSIs) carry significantly high risks of morbidity, mortality, and exorbitant health care costs from associated medical needs following injury.

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We therefore conclude that germline ENPP1 cysteine-specific mutations, primarily affecting the melanocyte lineage, cause a clinical spectrum of dyschromatosis, in which the p.Cys120Arg allele represents a recessive and more severe form of Cole disease. Fingerprinting and diversity of bacterial copA genes in response to soil types, soil organic status and copper contamination.

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In this paper we report the application of three different molecular markers, (i) RFLP of nodD genes, (ii) 16S-23S rDNA intergenic gene spacer fingerprinting and (iii) amplification fragment length polymorphism to S. Confirmation of tick bite by detection of antibody to Ixodes calreticulin salivary protein. The 24-hour ECG-blood pressure monitoring parameters did not differ significantly either between SH and healthy subjects while, in the ECH group, mean heart rate, maximum heart rate, and mean tachycardia episodes were significantly increased. Local dissolution of extracellular matrix by cultured human rectal adenocarcinoma cell line, RCM-1, was observed morphologically and confirmed by a quantitative assay using radiolabeled matrices. Myasthenia gravis patients with thymoma often have serum antibodies directed against human skeletal muscle.

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Our approach represents a versatile synthetic route for other metal nanomaterials with unprecedented control of their structure, creating a rational pathway for understanding and manipulating nanoscale chemical and physical processes as well as technological applications of metal NPs. Increased granulopoiesis after sequential administration of transforming growth factor-beta 1 and granulocyte-macrophage colony-stimulating factor.

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The influence of serum 25-hydroxy vitamin D levels on Helicobacter Pylori Infections in patients with end-stage renal failure on regular hemodialysis. Experiences of a pediatric nurse in a premature intensive care unit. Abnormalities of the proteins constituting the extracellular matrix have been shown to play important roles in the molecular pathogenesis of muscular dystrophies. Our psychophysical studies show, however, that performance of the human observer is indeed improved by deconvolution.

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The pathogenic bacterium Pseudomonas aeruginosa has the ability to cause severe acute and chronic infections in humans. BAEC grown on organ-derived biomatrices exhibit significantly altered binding intensities of Con A, RCA-I, WGA, and Neu-PNA: BAEC cultured on lung- or kidney-derived biomatrices express significantly stronger binding affinities for Con A and RCA-I than BAEC grown on liver-derived biomatrix or tissue culture plastic. In the presence of these sera, secondarily non-resistant strains of Streptococcus pyogenes were capable of vigorous growth and anti M 12 bactericidal activity was impaired.

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The thresholds of the receptor endings were twice as high in the hypertensive as in the normotensive rats (10.2 and 4.6 mm Hg, respectively). Anti-alpha-inhibin, an antibody directed against a peptide hormone, has been shown to be a useful diagnostic aid in surgical pathology material for the identification of sex cord-stromal neoplasms and recently has been described in adrenocortical carcinoma (ACC). We therefore investigated whether habitual physical activity influences the response of BMD to tibolone in postmenopausal women.

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The glycine singlet is overlapped by the larger signal of myo-inositol. Noncognate substrates lacking these interactions undergo slow base flipping, and fluorescence tracking of the catalytic loop corroborates the NMR evidence of a loose, nonspecific binding mode prior to base flipping and subsequent closure of the catalytic loop. The values obtained for the organic compounds (HCH, HCB, PCBs, DDT) depend upon the place and year of sampling and are compared to values found by other authors for the mussel M. These data support the hypothesis that calcium plays a role in increased cerebral endothelial permeability in hypertension.

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Astrocyte lipoproteins, effects of apoE on neuronal function, and role of apoE in amyloid-beta deposition in vivo. Although the function of these proteins had heretofore not been established, interest in the p63 polypeptide stemmed from its sperm-specific expression and its striking occurrence as a net charge variant among several insect species surveyed, using two-dimensional gel electrophoresis. The MS fragmentation pathways of the five iridoid glycosides were also studied. Eighty-five percent of the wounds were successfully treated with this flap, with minimal donor-site morbidity.

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Traumas in which a foreign body is propelled into the eye with high energy are most likely to penetrate the sclera. Only a few weeks later, the House of Commons Special Committee on Non-Medical Use of Drugs released its report, which contained a number of recommendations to the Correctional Service of Canada. Interphysician agreement in the diagnosis of subtypes of acute ischemic stroke: implications for clinical trials.

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Treatment of Df-stimulated PBMCs with a high dose, but not a low dose, of interleukin-4 stimulated production of Df-specific IgE by PMBCs from healthy persons or patients with asthma. Sulfhydryl modification of V449C in the glutamate transporter EAAT1 abolishes substrate transport but not the substrate-gated anion conductance. Delta 9-tetrahydrocannabinol, the principal psychoactive component of marijuana, exerts a variety of effects on the CNS, including impaired cognitive function and neurobehavioural deficits. All variants were specific for the sn-1 acyl ester bond of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine.

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Poly-Arg and poly-Lys showed predominantly competitive inhibition kinetics, although decreases in the k(cat) values for the chromogenic substrate S-2288 were also observed. We treated two tophaceus deposits on the left heel with the CO2 laser and conventional enucleating surgery. Sub-Saharan Africa is the only region in the world where the proportion of underweight children has stagnated and the absolute numbers have actually increased in the last decade. Likewise, women who had their first child at a young age performed significantly worse on each of these tasks, as well as on a measure of global cognitive function.

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Caffeine is a widely used stimulant with potentially beneficial effects on cognition as well as vasoconstrictive properties. The present study sought to evaluate the cytotoxic and genotoxic effects of chronic PCB exposure on fetal cells during pregnancy. According to anecdotal reports, it may be associated with use of oral contraceptives and hormone replacement therapy. To evaluate compliance with national guidelines concerning the diagnosis and treatment of malaria at Souro Sanou university hospital in Bobo-Dioulasso.

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Covering the urethral suture with a padding flap of vascularized preputial tissue helps avoid fistula formation. The steroid effects are thought to be mediated by binding of steroids to specific sites on GABA(A) receptors. Dry eye syndrome has significant economic implications, including costs associated with increased health care utilization, missed school and work, and leisure and quality-of-life issues.

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This work was done in order to develop a versatile coating for titanium-based orthopaedic implants that acts as both an effective bioactive surface and an effective anti-corrosion barrier. Comparative analysis in cases where analysis by the ITS was ambiguous clearly revealed the IGS1 region to be a more discriminatory tool in the typing of P. In the heart, rapid pacing rates may induce alternations in the strength of cardiac contraction, termed pulsus alternans. Laboratory diagnosis is important because the virus can cause disease that is clinically indistinguishable from other pox-like illnesses, particularly smallpox and chickenpox. With all polymers used, sub-130 nm p-THPP-loaded nanoparticles with similar drug loadings and entrapment efficiencies were produced using the emulsification-diffusion technique.

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When extracted membranes were reconstituted with dolichol or cholesterol, the original lower degree of contraction was reestablished. The recent development of an enteric-coated cysteamine formulation makes cysteamine more patient friendly and will extend its applicability for both old and new indications. pallidum studied were the high-rabbit-passage Nichols and the low-rabbit-passage KKJ. Annular morphology and mobility of the leaflets appeared normal with excellent leaflet coaptation.

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Therefore consumption of antibiotics and antifungals alone cannot explain the selection of resistant bacterial and fungal mutants and other factors have to be investigated. Climate policies accelerate both improvements in EF and the adoption of renewable technologies, resulting in considerably lower primary energy demand and GHG emissions. All clinical MRSA isolates for the period October 1990 through March 1995 underwent susceptibility testing to mupirocin.

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Reliance on behavioral endpoints in neurotoxicology risk assessment will likely increase in the future. Collectively, these data confirm a role for Nth in base excision repair in mycobacteria and further highlight a novel interplay between the Nth and Nei homologues in spontaneous mutagenesis. Optimal timing of surgery after a traumatic spinal cord injury (SCI) is one of the most controversial subjects in spine surgery. The full functional implications of ligand-stimulated complex formation are difficult to discern intuitively.

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The gnotobiotic piglet model is useful for delineation of the role of suspected bacterial virulence factors (i.e., motility and urease production) in gastric colonization and for preclinical determination of the efficacy of various antimicrobial substances. lovaniensis were made in inoculated samples of natural water from eight rivers in France and the United States.

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The anatomical relation between the bursa and the hip, and related pathological conditions are reviewed. In this study, the effects of mono-varietal cultivars of durum wheat on pasta quality were evaluated in order to find a good balance between nutritional and sensory properties of the final product.

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CSF samples from 500 patients with HIV infection and CNS symptoms were examined by PCR. In this procedure, the control liver showed normal hepatocytes with centrally placed nuclei, and the PB-treated hepatocyte showed degeneration of cytoplasm and nucleus, necrosis and fragmentation of nucleus, and pushing of nucleus to periphery. We reviewed the literature and identified relevant published studies. This review focuses on the complex regulatory mechanisms by which pRb-family proteins tell genes when to switch on and off. A multiplex reverse transcription-PCR technique was developed to simultaneously detect BNYVV, BSBV, and BVQ, together with their vector, P.

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Role of native disulfide bonds in the structure and activity of insulin-like growth factor 1: genetic models of protein-folding intermediates. The Diabetes Control and Complications Trial demonstrated that tight control of diabetes management greatly reduces the risk of microvascular complications of diabetes. Development of process analytical methods together with new data visualization algorithms creates new tools for in-process control of the fluidized bed granulation.

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Microarray-based gene expression profiling has had a major effect on our understanding of breast cancer. Constitutive DPP-IV activity was similar in polyps and turbinates cells. pylori ATCC43504 is caused by the insertion of a mini-IS605 sequence and deletion of sequences in an oxygen insensitive NAD(P)H nitroreductase encoding gene (rdxA).

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A survey of 122 otolaryngologists identified 21 ear injuries resulting from ear candle use. The resistance test by insufflation of atmospheric air and tensile strength showed higher average of pressure on the 7th day and breaking strength in the time periods for the aroeira group. HPLC method for identification and quantification of benzimidazole derivatives in antiparasitic drugs. This study was to evaluate the short-term and long-term efficacy and toxicity of the humanized anti-EGFR monoclonal antibody h-R3 in combination with radiotherapy for locoregionally advanced nasopharyngeal carcinoma (NPC). Induction of exogenous c-Fos in quiescent AT9.2 cells caused accelerated S-phase entry following serum stimulation, resulting in enhanced growth rate.

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Estrogen synthesis in the spinal dorsal horn: a new central mechanism for the hormonal regulation of pain. This investigation shows that, in most cases, the floor cleaning procedure of typical restaurants could be improved, resulting in a better cleaning efficiency and a better floor friction. Environmental classifications are obtained from hits against a custom database, MetaGenomes On-Line, which contains 49 million predicted environmental peptides. However, similarity was far more pronounced between related pairs than between unrelated pairs. Developing relationships: arterial platelet adhesion, glycoprotein Ib, and leucine-rich glycoproteins.

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Although data from this study confirmed that the 15CBS is a reliable procedure within people with COPD, further modification is required to increase the validity and discriminative ability of this instrument. However, further developments of KDD methods are still expected to better adapt to the features of TCM. Intraosseous transfusion in an anesthetized swine model using 51Cr-labeled autologous red blood cells. Dorsal expansion of the mouth cavity can only be powered by the epaxial muscles, but both the sternohyoid, shortening against an immobile pectoral girdle to retract the hyoid, and the hypaxial muscles, shortening to retract both the pectoral girdle and hyoid, could contribute ventral expansion power.

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To develop photosynthetic cell factories, it is important to improve diatoms for value-added products. The resultant enhancements can benefit the doctor and patient as well as offer the manufacturer a marketing opportunity to increase sales and profitability. The disease is probably caused by the accumulation of lithiasis material from the otolithic membrane of the utricle.

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In addition, a significant decrease of sleep inertia was observed upon the morning awakening of the second deprivation night for the measure of performance speed, and a significant increase of sleep inertia upon the morning awakening of the recovery night for the measure of performance accuracy. Economic projections based on proximal-distal modeling techniques may be used in cost-benefit analyses when information is unavailable for certain long-term outcomes data in adulthood or to build entire cost-benefit analyses.

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This synergy for NO production corresponded to the results of iNOS mRNA expression analyzed by Northern blotting. Dental follicular tissue: misinterpretation as odontogenic tumors. Coronary artery bypass was performed using moderate hypothermia and oxygenated crystalloid cardioplegia. In our second case, the association of the signet ring cells with lutein cells and the positive staining of the signet ring cells for inhibin and steroidogenic factor 1 confirm that in some instances signet ring cells are derived from lutein cells.

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The effects of suprefusing glucose free medium (aglycaemia) and superfusing glucose free and O2 free medium (ischaemia) were examined on these reflexes. Subgingival plaque samples from 167 subjects with varying degrees of periodontal breakdown were obtained and cultured for the presence of P.

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Our case describes a self-limited biopsy-proven membranous nephropathy after intravitreal bevacizumab injections. Bilateral osteochondral defects (2.7 mm in diameter and 5 mm in depth) were created on the femoral condyles of twelve New Zealand White rabbits. However, the in vivo consequences of IKK activation on the onset and progression of acute pancreatitis remain unclear.

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An additional group was given 300 mg/kg body weight/day zidovudine (AZT) as a negative control. In contrast, in 4 of 8 trials involving prostate cancer patients, isoflavones significantly favorably affected PSA although in no studies was there an absolute decrease in PSA concentrations. Lifestyle modification in colorectal cancer patients: an integrative oncology approach.

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Metastatic spread of prostate adenocarcinoma to the temporal bone is very rare. We examined hepatic cytochrome P450 (CYP) induction in rat foetuses and neonates by phenobarbital administered through placenta or breast feeding. Data were recorded retrospectively on demographics and clinical information, seizure types and syndrome diagnosis, antiepileptic drug treatment details, and remission rates.

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These results suggest that persistent copper accumulation after toxic necrosis of tubules is the major cause of spontaneous renal carcinogenesis in LEC rats. The aim of this study was to test the prognostic influence of p53 nuclear overexpression in colorectal carcinoma. It is suggested that surgeons should be aware of the existence and treatment of these forms. Suggestions about the aetiology of this localized hypoplasia range from genotypic factors to environmental conditions and systemic effects. This study demonstrated the close relationship between acute cholangitis in hepatolithiasis and enteric bacteria and also displayed the detailed antibiotic sensitivity results.

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Glutaraldehyde pretreated porcine valves were studied before and after implantation in rats by X-ray, calcium (Ca) and phosphorus (P) measurement, Fourier Transform Infrared (FTIR) spectroscopy, SDS-PAGE and 45Ca ligand blotting of the extracted proteins. To corroborate this possible mechanism of action, we investigated the binding of 3H-dexamethasone to local glucocorticoid receptors in synovial tissue from 3 patients with active RA, before and 14 days after a single intraarticular injection of progesterone.