Lamotrix was originally developed as an antiseizure drug because of its ability to reduce folate levels. At the time of the drug's development, it was thought that folate depletion would treat epileptic activity. Although this is now known to be incorrect, the drug did serendipitously treat seizures effectively. Currently, pharmacologists understand that Lamotrix reduces neuronal activity via a variety of mechanisms. The most commonly accepted mechanisms of action are enhancement of sodium channel inactivation and possible inhibition of synaptic glutamate release. In early studies, patients with epilepsy who were taking Lamotrix reported increases in a subjective sense of well-being, and this led to its exploration as a psychotropic drug. From a neuropsychiatric standpoint, Lamotrix appears to inhibit uptake of serotonin, dopamine, and noradrenaline.
Other names for this medication:
Lamotrigine,
Lamictal,
Daksol,
Epitec,
Flamus,
Labileno,
Lafigin,
Lamal,
Lambipol,
Lamez,
Lamictin,
Lamidus,
Lamirax,
Lamitor,
Lamitrin,
Lamogine,
Lamolep,
Lamotrigin,
Lamotrigina,
Lamotrix,
Lomarin,
Meganox,
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