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Conversion to rapamycin in renal allograft recipients with biopsy-proven calcineurin inhibitor-induced nephrotoxicity. Effect of ascorbic acid on the mortality of Leghorn-type chickens due to overheating. Alterations in stress responsivity may be important in the vulnerability to become cocaine dependent. We present here a patient who underwent an anterior L4 corpectomy with Harms cage placement and who later developed a fracture of the lumbar titanium mesh cage (TMC).

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We previously demonstrated the efficacy of local rhIGF-1 application via hydrogels before noise exposure for prevention of NIHL. The association of insulin with noncardiovascular mortality was U-shaped. Graphite nanoplatelet chemical cross-linking by elemental sulfur. Restoration of viability resulted, at least in part, from maintenance of replication protein activity at high temperature. In neurons, the carboxyl-terminal tail domains of the NF-M and NF-H subunits of heteropolymeric neurofilaments (NFs) are highly phosphorylated by proline-directed protein kinases.

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However, both the core domain (Arg(141)-Ala(766)) and full-length protein mutually interacted. Modeling potential responses to smallpox as a bioterrorist weapon. This study evaluated the clinical incidence and characteristics of spinal dissemination and the effect on outcome. Study on the behavior of basophilic granulocytes in women in normal and pathological conditions This is the first report of RFP-induced pneumonitis occurring during adjunct steroid therapy.

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We created a mouse model that linked maternal exposure to DEPs with asthma susceptibility in offspring. Chondrogenesis of adipose derived stem cells induced by misshapen auricular chondrocytes from microtia in vitro

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When prescribed as an antidepressant, bupropion is generally considered to have a lower relative risk of inducing mood shifts. Viral titers in eyes and ganglia of IFN-gammaR-/- mice were not significantly different from congenic controls.

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Its peptide structure requires intrathecal administration for effectiveness, therefore we determined the intrathecal pharmacokinetics of CGX-1160 after bolus dose and multiple day infusions to beagles. Relationship between plasma homocysteine levels and brain atrophy in healthy elderly individuals. The lipoyl-lysine residue (Lys42) is located in a tight turn at a corner of one sheet, the N-terminal and C-terminal residues of the domain are close together in two adjacent beta-strands in the other.

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In anaerobic batch cultures, the maximum specific growth rate of the adh3 delta mutant (0.22 h(-1)) was substantially reduced compared to that of the wild-type strain (0.33 h(-1)). Changes of attitudes and patronage behaviors in response to a smoke-free bar law. A highly polymorphic meiotic recombination mouse hot spot exhibits incomplete repair.

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In order to secure a safe and effective airway in such a patient, we should diagnose accurately and select the methods of securing the airway earlier in the post-traumatic period. The main finding from this study was that PPF was enhanced during presynaptic inhibition of compound Ia EPSPs. A pencil and paper survey was administered to people attending events associated with the Feast GLBTI festival in Adelaide in 2004 and good participation rates were obtained. STS did not greatly affect the plasma concentration of total Pt when it was administered at a 100-fold molar ratio to CDDP, yielding only p poor effect. Elevated levels of suPAR are, independently of established cardiovascular risk factors, associated with an increased incidence of CVD in elderly subjects.

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Furthermore, rather than merely stabilizing the gene expression changes that are driven by developmental transcription factors, there is emerging evidence that chromatin regulators have multifaceted roles in cell fate decisions. Drug susceptibility testing was performed using the indirect proportion method.

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The questionnaire asked the subjects to rank 12 measures of health care outcomes. Until recently, a successful outcome in cases of canine SBF was possible by administering a potentiated amoxicillin, a first generation cephalosporin or a potentiated sulfonamide.

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Thirty pregnant women in the last trimester were interviewed three times using a 24-hour dietary recall with weighing of foods and recipes of dishes. To investigate the mechanisms involved in hypoxia-induced metastasis and hypoxia-mediated chemokine receptor CXCR4 expression, we used lentiviral vector mediated RNA interfering (RNAi) to knock down expression of HIF-1alpha or HIF-2alpha in two NSCLC cell lines to investigate HIF-dependent invasion, migration and adhesion. Five essays in this issue of the Journal of Medicine and Philosophy are introduced and summarized to emphasize the real differences in medical ethical theories and the challenge presented by a comparative study of their competing claims. The growing number of DNA helicases implicated in human disease suggests that their vital specialized roles in cellular pathways are important for the maintenance of genome stability. A comparison of these results from linear system theory with the nonlinear dynamical behavior of the CNS was performed.

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Genetic variability of human diamine oxidase: occurrence of three nonsynonymous polymorphisms and study of their effect on serum enzyme activity. Anti-apoptotic activity seems to balance pro-apoptotic activity.

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SIT generally does not bear any pathophysiological significance, and the survival rate of patients with SIT does not differ from that of healthy individuals. Brain cytosolic NO synthase activity was significantly reduced with increasing age.

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All patients were tested with the same comprehensive battery of paper-and-pencil and computerized tasks assessing numerical abilities and calculation. The Southern blots also showed that there is at least one triticin gene located on the short arm of each of the homoeologous group 1 chromosomes (1A, 1B, 1D), although till now no triticin protein product has been identified for the chromosome 1B. When compared to conventional organic matrixes (e.g., 2,5-dihydroxybenzoic acid), AuNPs as LDI matrixes provide a number of advantages, including ease of preparation, selectivity, sensitivity, and repeatability. Finally, I explore various functions that an internal morality might serve, concluding with the observation that, while there may be a core of good sense to the notion of an internal morality of medicine, our expectations for it must be drastically lowered.

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PTSD pos had a thinner rostral anterior cingulate and insular cortex but no hippocampal volume loss. During terrorist-related multiple-casualty events (TMCEs), the role of the surgeon expands beyond providing traditional trauma care. Physicians who do not possess these traits will not likely attain high ratings, while having these core traits does not necessarily ensure high patient satisfaction.

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Findings of this study could be used to provide more direction for future research to facilitate innovation, improve health outcomes or address priority health problems. These results suggest a compartmentalization of cyclin E functions in the oncogenic process. Electrocardioversion in the preoperative treatment of urologic patients with chronic supraventricular arrhythmia Targeting the autophagy pathway in a multi-modal fashion might therefore offer a clinical option for treating recalcitrant SOC.

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These unique capabilities will continue to assure ongoing clinical relevance of radionuclide methodology, as is the case in the assessment of heart disease in adult cardiology. The role of HPV infection in cases of vulvar papillomatosis and vulvar vestibulitis syndrome is still unclear and data from the literature is controversial. Ninety to one hundred five days later these rats were compared to control rats in acquisition of passive avoidance and in open field activity. Eighteen patients aged 41 to 74 years had inferior epigastric artery grafts to 19 coronary arteries. Plasmid pKN62 harbors the fragment located in between the left PstI and EcoRI cleavage sites on Mu DNA, allows plating of superinfecting Mu phages, but does not express the killing function.

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Although the incidence of electrical burns is not very high this incidence is rising in India. To assess the characteristics and long-term outcome after surgery in patients with multiple endocrine neoplasia type 1 (MEN1)-associated insulinoma. Listening to anonymous taped sessions allowed for the possibility of a freer climate for discussion, as none of the seminar participants had a personal relationship with the taped analyst. Massive pulmonary embolism is relatively rare but a potentially life-threatening condition. These changes are accompanied by a reduced TLR7-mediated cytokine response.

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Those reporting hallucinations all wished to remain in the study. Effects of leukocyte elimination before storage on quality of red blood cell concentration Postpartum depression (PPD) is the most common psychiatric complication observed in women after they give birth. Treatment of steroid-resistant acute GVHD with OKT3 and high-dose steroids results in better disease control and lower incidence of infectious complications when compared to high-dose steroids alone: a randomized multicenter trial by the EBMT Chronic Leukemia Working Party. In conclusion, Firmicutes and Bacteroidetes were identified abundantly when the geese was fed with all-grass feed and high-grain feed, respectively.

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The clinical, radiological and light microscopic features of this case are described. This should be taken into account especially in the management of midline tumors where a seemingly unilateral drainage at scintigraphy warrants nevertheless a surgical assessment of the mute groin. Self potential generated by unscreened fixed charges at the membrane interface of the erythrocyte perturbs the lipid bilayer.

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The common requirements are (1) the accurate delivery of the modality and (2) the functional importance of targeting the biologic basis rather than the anatomic structure--hence the term biosurgery. Physicians should be able to diagnose and manage the six recognized types of spontaneous abortion: threatened, inevitable, incomplete, complete, missed and septic. Now, a new study uncovers a major role for Polycomb components of the PRC1 complex in organizing physical networks of genes that are co-repressed to maintain pluripotency. A 63-year-old patient who had undergone atrial septal defect surgical repair received implantation of a single chamber VVI pacemaker for long RR intervals during atrial fibrillation.

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This study suggests that repeated, as needed, DEX injections for CME associated with RVO may be performed. Our data suggest that GSTP1 gene polymorphisms may contribute to the development of T2DM in Romanian population.

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Commissioning an image-guided localization system for radiotherapy. Both resistance- and endurance-type exercise reduce the prevalence of hyperglycaemia in individuals with impaired glucose tolerance and in insulin-treated and non-insulin-treated type 2 diabetic patients. Furthermore, intracellular sodium and its transport mechanisms have been implicated in the pathogenesis of hypertension associated with dietary sodium.

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Although many of these techniques are suitable for clinical adaptation, selection of a method for use in a clinical laboratory will depend on the budget and availability of equipment and expertise. To test the effectiveness of a psychosocial intervention to improve early adherence among older patients whose primary care physician newly initiated an antidepressant for depression. Sodium chloride enhances cadmium tolerance through reducing cadmium accumulation and increasing anti-oxidative enzyme activity in tobacco.

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Esophagofundorrhaphy, fundoplication and valvular gastroplication in sliding hiatal hernia Endometrial and cytological studies of intrauterine contraceptive devices. Because non-invasive mechanical ventilation (NIV) is increasingly used, new devices, both ventilators and interfaces, have been continuously proposed for clinical use in recent years. Perfusion from the femoral artery is commonly used in the open proximal method of performing distal aortic arch aneurysm repair or Stanford type B aortic dissection repair under circulatory arrest through left thoracotomy.

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Duloxetine inhibited ex vivo binding to rat 5-HT transporters and NE transporters with ED(50) values of 0.03 and 0.7 mg/kg, respectively, whereas venlafaxine had ED(50) values of 2 and 54 mg/kg, respectively. However, an antagonistic effect of isoallopregnanolone to allopregnanolone on the GABA(A) receptor has been shown in animal and in vitro studies. Understanding why we agree on the evidence but disagree on the medicine. Converting this raw sequence information into a better understanding of the biology of bacteria involves the identification and annotation of genes, proteins and pathways. Biochemical properties of liver peroxisomes from rat, guinea pig and human species and the influence of hormonal status on rat liver acyl-CoA oxidase mRNA content.

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Intervention group mother-child pairs will be instructed to exercise every other day while watching the video program over the next seven weeks. In Ayrshire they seem to have learned that their participation mattered.

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The majority of children aged 5-12 live close to school but only a small minority of students walk the distance. These aberrant genetic alterations, when assembled in a single breast cell, disrupt the control system to the extent that the cell functions autonomously in an erratic and irregular manner. Models have been proposed that exploit each of these two views, and psychophysical data exist in favor of and against each view. No change in susceptibility to nitrogen narcosis was seen in divers in chamber tests at 460 KPa.

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Inactivation of the core cell cycle regulators, including the G1/S regulators E2F1, Cyclin E, Cdk2, and PCNA, and the G2/M regulators Cyclin A, Cyclin B, and Cdk1, mimic RPA loss-of-function phenotypes, suggesting that cell cycle progression is required for both maintaining neuroepithelial cell identity and suppressing neuroblast formation. CT angiography of stented carotid arteries: comparison with Doppler ultrasonography.

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The sole species of scops owl known from Lombok has long been assigned to the widespread Moluccan Scops Owl Otus magicus on the basis of superficial similarities in morphology. alpha-Tocopherol is presumed to occur in association with intracellular membranes, but the techniques on which this presumption was based have been insufficiently sensitive to allow its confident acceptance. We also found that the extent of tyrosine phosphorylation of the adaptor protein p95vav was similar in activated T lymphocytes from elderly and young subjects. Given the potential roles of kininogen in vascular injury and inflammation, we have investigated the regulation of kininogen gene expression in the MCT-induced pulmonary hypertensive rat model.

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Double 2s-1s resonance in LO-phonon-assisted secondary emission of quantum-well structures. The objective of the study is to determine if tamsulosin initiated in the emergency department (ED) decreases the time to ureteral stone passage at 1 week or time to pain resolution, compared to placebo. Selective attenuation of neuropeptide-Y-mediated contractile responses in blood vessels from patients with diabetes mellitus. Four children at the higher dosage level were also studied after an equal IV dose.

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Identification of potential therapeutic target genes and mechanisms in non-small-cell lung carcinoma in non-smoking women based on bioinformatics analysis. For those reporting higher levels of impulsivity at baseline, full-time employment was associated with an increase in drinking variables (quantity and frequency), whereas drinking was unaffected by full-time employment status among those reporting lower levels of impulsivity.

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The diagnostic value of the triiodothyronine-suppression-tes in thyroid gland diagnosis with radioactive iodine Incidence, etiology, and outcome of stroke in patients on continuous ambulatory peritoneal dialysis.

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However, this effect was primarily due to the cytotoxic effect of higher saquinavir doses. Impact of retraction of vas deferens in postradical prostatectomy inguinal hernia. Uncoupling in the wall of the cartilaginous bronchus of the pig produced by smooth muscle contraction.

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Menthol derivative WS-12 selectively activates transient receptor potential melastatin-8 (TRPM8) ion channels. Assessing the survival of transgenic plant DNA in the human gastrointestinal tract. A new method was developed to evaluate beef tenderness by applying air flow pressure on a beef sample surface and using a laser displacement sensor to measure the associated surface deformation as influenced by the beef viscoelasticity.

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Using logistic regression analysis, there was a significantly increased risk of developing psychoorganic syndrome from solvent exposure. Statements functioning as suggestions may induce positive or negative perceptual responses and experiences. Thulium 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrakis(methylene phosphonate) as a 23Na shift reagent for the in vivo rat liver.

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In method A the formalin-fixed tissues were grossed, proper sections were taken, processed in an automatic tissue processor, embedded in paraffin blocks, and microtomic sections were made. In contrast, inclusion of alphaB-crystallin or HSP27 prevented gel formation but not filament assembly. MitraClip (Abbott Vascular) therapy has been reported to be a safe and effective treatment for mitral regurgitation, even when the commissures are targeted. This property allows also the association of cytoplasmic enzymes and multimolecular complexes with the cytoskeleton, facilitating metabolic channelling and the localization of these complexes in specific subdomains of the cytoplasm. We have studied the morphological consequences of implantation into the injured adult rat spinal cord of fibroblasts derived from the meninges overlying the cerebral cortex.

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Here, we used shape information from subcortical structures to test a recently developed feature-selection method based on regularized random forests to 1) classify depressed subjects versus controls, and 2) patients before and after treatment with electroconvulsive therapy. TAS level in the cancer group was decreased when compared to the controls. Characterizing structural features of cuticle-degrading proteases from fungi by molecular modeling. All in vivo and in vitro models studied pointed to relevant contributions of the fraction of polyphenols and flavonoids.

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MAIN PATIENT PARAMETERS AND OUTCOME MEASURES: For each patient, the following data were recorded: age, risk factors, other systemic findings, dates of AIDS and CMV retinitis diagnoses, stage of AIDS, extent of the retinitis, CD4 lymphocyte count at the time of diagnosis of retinitis, visual acuity, clinical evolution of the ocular infection, therapy, complications caused by the treatment, development on nonocular CMV, and the use of zidovudine or didanosine during the study period. Very recently, the combination of cisplatin with the taxane paclitaxel was shown significantly more efficacious than the old standard of platin plus cyclophosphamide with regard to response and survival rates representing actually the therapy of choice for the primary therapy of advanced ovarian cancer. However, many exciting new agents are on the horizon that offer hope to further advance the progress made to date although further confounding the questions already answered. Mucus and Mucins: do they have a role in the inhibition of the human immunodeficiency virus?