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Novamin (Prochlorperazine)

Novamin is the maleate salt form of Novamin, a synthetic, piperazine phenothiazine derivative with antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Novamin binds to and blocks the postsynaptic dopamine D2-receptor in the chemoreceptor trigger zone (CTZ) of the brain and may prevent chemotherapy-induced emesis. Novamin maleate also blocks anticholinergic and alpha-adrenergic receptors. Its antagonistic actions on the alpha-1 adrenergic receptors results in sedation, muscle relaxation, and hypotension.

Other names for this medication:
Prochlorperazine, Compazine, Antinaus, Buccastem, Carmetic, Darbazine, Dhaperazine, Emetiral, Emidoxyn, Mitil, Nautisol, Novamin, Prochlor, Proclorperazina, Procomp, Promat, Roumin, Stemetil, Stemzine, Steremal, Vergon,

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DNA mimics of red fluorescent proteins (RFP) based on G-quadruplex-confined synthetic RFP chromophores. It is highly accurate for differentiating between benign and malignant lesions and for predicting T stage, but is limited for predicting nodal status. Adrenal pheochromocytoma mimicking small cell carcinoma on fine needle aspiration biopsy. Modeling the VEGF-Bcl-2-CXCL8 pathway in intratumoral agiogenesis.

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In the present studies, the amino acid constituents of the GLUT-4 NH2-terminal targeting domain have been identified. Acute and chronic toxicities of tributyltin to various life stages of the marine polychaete Hydroides elegans. Technetium-99m-labeled platelets: comparison of labeling with a new lipid-soluble Sn(II)-mercaptopyridine-N-oxide and 99mTc-HMPAO. Due to CT evidence of hemoperitoneum, the patient received an emergent laparatomy.

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Additional diagnostic value of integrated analysis of cardiac CTA and SPECT MPI using the SMARTVis system in patients with suspected coronary artery disease. In the present study, we examined the effects of IMP on the Cl(-) secretion produced by isoproterenol (ISP), a beta-adrenergic receptor (beta-AR) agonist, in Calu-3 human airway cells. Our objective is to present an unusual acute hyperammonemic crisis suggesting a key role of brain glutamine to mediate ammonia neurotoxicity and the interest of intracerebral pressure (ICP) monitoring to maintain adequate cerebral perfusion pressure and to prevent neurological damages. The first case is about a band-3 protein defect, the second deals with an hereditary dehydrated stomatocytosis.

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Initiation and maintenance of callus tissue culture of Uncaria elliptica for flavonoid production. Rehabilitation and workplace adjustment to reduce sickness absence and improve work ability should be a long-term concern. Pressure-temperature phase diagram of solid hydrogen sulfide determined by Raman spectroscopy. A better understanding of the molecular biology of non-small cell lung cancer with multiple driver genomic aberrations will assist in determining optimal treatment.

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To evaluate the effects of intravenous magnesium sulfate (Mg(2)SO(4)) administration on ischemia-reperfusion injury of the spinal cord. Our results suggest a model in which the TRAIL decoy receptors may be induced by p53, thereby attenuating an apoptotic response that appears to involve KILLER/DR5. All patients noted an immediate reduction in pain and in 2 patients the TC rapidly resolved. Preclinical studies suggest that PDE4 could be a therapeutic target for several classes of substance use disorder.

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We characterized angiotensin II receptor subtypes in the conduction system of the rat heart using quantitative autoradiography. Human infection is mainly transmitted from cattle, goats and sheep. We therefore conclude that this study might contribute to the development of a new line of anti-tuberculosis agents.

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Hyperbaric oxygen (HBO2) reduced the incidence of cognitive sequelae 6 weeks after carbon monoxide (CO) poisoning compared with normobaric oxygen (NBO2). Proceedings of the 24th International Information Processing in Medical Imaging Conference, IPMI 2015, June 28-July 3, 2015, Isle of Skye, United Kingdom. Instead of proposing a single definition of mindfulness, we interpret it as a continuum of practices involving states and processes that can be mapped into a multidimensional phenomenological matrix which itself can be expressed in a neurocognitive framework. A DNA microarray containing 4,020 genes from this organism was constructed to explore anaerobic gene expression patterns on a genomic scale.

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Explanation of ethical principles in child and adolescent psychiatric treatment Therapeutic applications of drugs acting on peripheral dopamine receptors. In this system, it has been demonstrated that alpha 2 agonists have inhibitory properties, but DA2 agonists are inactive.(ABSTRACT TRUNCATED AT 250 WORDS) The optical absorption spectra revealed a well-quantized electronic structure and a systematic red-shift of the absorption onset with increasing gold core size, which was manifested in a color change with particle size.

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A selective biopsy of the encompassed and compressed nerve fascicles demonstrated both myelin loss and axonal injury. Plasma concentration profiles after pre-operative rectal administration of a solution of paracetamol in children. Though usually straightforward, treatment of dermatophytosis becomes notably challenging in certain population groups - pregnant women, children, and elderly.

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45-XO gonadal dysgenesis with predominantly monolateral manifestation This study had a dual purpose (1) to identify variables associated with perceived work role performance (WRP) among 315 mental health professionals (MHPs) in Quebec and (2) to compare variables related to WRP in MH primary care teams (PCTs) and specialized service teams (SSTs), respectively. Comparison of the Biochemical Recurrence risk between Radical Prostatectomy and Brachytherapy in the treatment of low- and intermediate-risk prostate cancer

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Intracerebral Distribution of a-Pinene and the Anxiolytic-like Effect in Mice Following Inhaled Administration of Essential Oil from Chamaecyparis obtuse. Water immersion may cause physiological changes within the body that could improve recovery from exercise. Regional intra-arterial chemotherapy may provide high levels of cytostatic concentrations within the tumor and, simultaneously, a low rate of systemic side effects compared with systemic administration of anti-neoplastic drugs. Naltrexone failed to block the rate-decreasing effects of d-propoxyphene. In 9 of the 12 farms studied only 2-3 REA patterns were detected, with one clearly predominant pattern.

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PD-L1-blockaded DCs could enhance T lymphocyte proliferation, increase the secretion of IL-2 and IFN-gamma, and inhibit the production of IL-10. Our results give no evidence that HPA-1, -2, -3 and -5 alloantigens should be considered minor transplantation antigens in clinical bone marrow transplantation. Together with previous reported factors, CRP could serve as a potential tool to determine future treatment strategies for optimal individual palliation.

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Total rescue morphine consumption was reduced in the clonidine group, particularly at D1-D2, a benefit that was exclusive to the lumbar stenosis and lumbar fusion subgroups. To describe the clinical toxicity caused by oleoresin capsicum (OC) spray during law-enforcement action. Scalp hypothermia as a preventative measure for chemotherapy-induced alopecia: a review of controlled clinical trials. This study shows the role of female sex hormones in aggravating gingivitis to its peak in the 3rd trimester, even though the oral hygiene remains fairly good constantly.

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The videoradiographic examination described was designed for habitual snorers and sleep apnea syndrome (SAS) patients and was performed during wakefulness and sleep. Rats were intoxicated with two different S-aminoalkyl-phosphonothioate cholinesterase inhibitors, viz.

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Role of epithelial basement membrane of the small intestine in providing immunologic homeostasis This study was undertaken to assess whether plasminogen activator (PA) induction in macrophages exposed to chrysotile fibers is mediated by protein kinase C (PKC) activation.

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When the primary 3LL was irradiated, tumour size was unaffected but the number of pulmonary metastases was reduced. To investigate the role of sensory cues in ordinal number processes, we manipulated both dimensions orthogonally. These benign complications are frequently described in literature, but adenocarcinoma in the colonic graft is a rare complication.

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Orthogonal HPLC methods for quantitating related substances and degradation products of pramlintide. A reduction in the use of medication by patients after bariatric surgery has been reported for various drug classes.

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CAT expression for IL-8 promoter activity was higher in cell lysates stimulated with T. Molecular phylogeny of tephritid fruit flies in the Bactrocera tau complex using the mitochondrial COI sequences.

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Cellular knock-down of quinone reductase 2: a laborious road to successful inhibition by RNA interference. This study extends these findings to another realm of DA-related behavior, reward function.

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Given that stress exposure is a prominent risk factor for anxiety and trauma-related disorders marked by persistent, inflexible responses to threat, here we examined how acute stress affects the flexible updating of threat responses. The results showed that HY profoundly reduced the lytic activity of NK cells and demonstrated that this inhibition was transient and not due to an apoptosis-induced reduction of the number of effector cells. Erythrocytes aggregation in healthy donors at native and standard hematocrit: the influence of sex, age, immunoglobulins and fibrinogen concentrations. Three weeks of running wheel exposure improves cognitive performance in the aged Tg2576 mouse.

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Prediction of outcome and response to rehabilitation in patients with stroke can be difficult, especially in the elderly. Retrotransposon(-like) sequences in Aspergillus fumigatus have been used as typing targets through restriction fragment length polymorphism (RFLP)/Southern blotting approaches. Appropriate radiologic interpretation of the finding prevents overstaging of prostate cancer. A parameter-free geometric model for nuclear absorption is derived from microscopic theory.

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Cloning of the SAP6 gene of Metschnikowia reukaufii and its heterologous expression and characterization in Escherichia coli. Methotrexate, a folinic acid antagonist, has been used to treat patients with small unruptured tubal pregnancies.

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In nonstimulated IMCD cells the majority of AQP-2 staining was detected intracellularly but became mainly localized within the cell membrane after stimulation with AVP or forskolin. Overall, few sensors showed an exceptional and consistent performance, which can shed light on the fine spatiotemporal urban variability of pollutant concentrations. After the operation peritonitis have occurred in 19 patients, in 40--postoperative period course was without complications. The aim of this study was to evaluate the plasma exposure and urinary excretion of fentanyl and norfentanyl according to cytochrome P450 (CYP) 3A5 genetic polymorphism.

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Embryonal carcinoma (EC) cell lines expressed these transcripts at consistent levels and hLIF-M was generally the predominant LIF transcript in these cells. The term protocollagen has been used to describe the proline-rich and lysine-rich polypeptide or polypeptides that serve as substrates for the formation of hydroxyproline and hydroxylysine during the synthesis of collagen. The receptor for advanced glycation end products (RAGE) is a multiligand cell-surface protein and belongs to the immunoglobulin superfamily. In Experiment 1, monkeys engaged in item-based processing with a small training set size, and they progressively engaged in relation-based processing as training set size was increased. Using cells with acquired paclitaxel/cisplatin resistance, we elucidated effects of indirect NEAPP-activated medium (NEAPP-AM) exposure on cell viability and tumor growth in vitro and in vivo.

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Low-dose intradermal vaccination in the prevention of hepatitis B Among the measured cytokines, IL-6 could be the most reliable in vitro marker indicative of phototoxic potential, because it showed statistically significant increase only in case of concurrent exposure to chemicals and UVA. The calculations showed that the reaction between the reactant and SnCl(4), which generates 1-trichlorostannylbuta-2,3-diene via transmetalation, has a low energy barrier of 78.1 kJ.mol(-)(1). Additional capnographic monitoring of ventilatory activity resulted in improved detection of apnea. Urinary tract infections are caused primarily by uropathogenic Escherichia coli (UPEC), and indwelling catheters are usually colonized by UPEC biofilms tolerant to common antibiotics.

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Age variation in the frequency of lymphocytosis in the conjunctival fluid. To identify the potential markers related to NACT sensitivity of breast cancer, in the present study, we examined the protein spectrum of breast cancer tissues before and after NACT using surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF MS). We revised studies that focused on the components of the International Classification of Functioning, Disability and Health (ICF) in children with CP. However, this tumor rarely metastasizes to the eye and only a few cases of metastasis to the choroid have been reported. In the absence of mitogenic stimuli, cells normally arrest in G(1/0), because they fail to pass the G1-restriction point.

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CT and MRI Findings of Autoimmune Polymorph Bifocal Pancreatitis Mimicking Pancreatic Adenocarcinoma: A Case Report and Review of the Literature. Polycomb group (PcG) proteins are highly conserved chromatin factors that repress transcription of particular target genes in animals and plants. When in trans, type II and type III fpvA restored PVD production, uptake, growth in the presence of EDDHA and, in the case of type II fpvA, pyocin S3 sensitivity.

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