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Twenty-four hour recordings of colonic motility in patients with diverticular disease: evidence for abnormal motility and propulsive activity. Proteasome inhibition in combination with inhibition of transcription revealed that the observed up-regulation is mediated by coordinated transcriptional activation of the proteasome genes and not by post-transcriptional events. Scale-dependent interaction of fire and grazing on community heterogeneity in tallgrass prairie. Circular mitochondrial DNA from Xenopus laevis and Rana pipiens. Among 106 patients treated with conventional-dose methotrexate (MTX) following prior therapy with cis-diamminedichloride platinum (CDDP), six died with clinical manifestations of MTX toxicity.

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Some in vitro and in vivo studies with neutrons have shown increased carcinogenic effectiveness following low-dose-rate or fractionated irradiation compared to acute exposure in the low-dose range. Hydroxy radial involvement in retinol hemolysis of human erythrocytes in vitro.

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Omega-3 fatty acid modification of membrane structure and function. The program, called INPARANOID, was tested on all completely sequenced eukaryotic genomes. The prevalence of psychiatric disorders and mood disorders was higher in the IBS group than the control groups. The seminal vesicle appeared on the third day and divided into two sacs on the fourth day p.i. The data suggest that induction of tolerance to an autoantigen by peptide-loaded DCs requires presentation of antigen by iDCs and involves the generation of a high-level IL-10 and IL-5 immune response in DLN cells.

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Radioactive iodine treatment improved local control but did not not affect OS. Influence of humic substances on the removal of pentachlorophenol by a biomimetic catalytic system with a water-soluble iron(III)-porphyrin complex. The features that differentiated MS from TSP patients, apart from HTLV-1 status, included clinical evidence of cranial nerve involvement, more extensive abnormalities on the brain and cervical cord MRI and asymmetry of the VEP latency increase, all of which were more frequent in the MS group. Application of vacuum-assisted therapy in postoperative ascitic fluid leaks: an integral part of multimodality wound management in cirrhotic patients. Higher rates of concussions occur in games versus practice, and there was an overrepresentation of forwards injured versus defensemen or goaltenders.

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We find that many of the potentially vulnerable sub-structural interfaces tend to be protected in the fold interior, in many cases stabilised by disulfide bridges spanning the interface. In temperate ecosystems, acidic forest soils are among the most nutrient-poor terrestrial environments. CDNA cloning and characterization of S6 kinase and its effect on yolk protein gene expression in the oriental fruit fly Bactrocera dorsalis (Hendel). Before surgery, a standardized ultrasonographic examination of the CL, including B-mode and color Doppler ultrasonography measurements, was performed.

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Bone resorption by osteoclasts stimulates bone formation by osteoblasts. These findings might be related with edema of the ischemic region. Digitisation of images recorded on film is a crucial part of data acquisition in electron microscopy, particularly for electron cryo-microscopy of biological specimens where the contrast and signal-to-noise ratio are low. Effects of acute administration of the hydroalcoholic extract of mate tea leaves (Ilex paraguariensis) in animal models of learning and memory. We report the results of our own renal transplantation program with special emphasis on vascular techniques, pediatric transplantation, and the management of complications.

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Consideration of these parallels enables us to make testable experimental predictions about Notch and C-signaling. Microbiological and immunological aspects of experimental periodontal disease in rats: a review article. Scrambler Therapy is an efficient and safe alternative for several different types of refractory chronic neuropathic pain, with a very rare possibility of adverse events. These results suggest that the major satellite DNA was amplified with base substitution in A.

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Concerns have been raised regarding the possibility of a predisposition of KD to premature atherosclerosis later in life. In the literature wide discussion about the basic theories of definition, physiology, pathophysiology, diagnostics of the given condition take place. The trioma cell is a polyvalent vaccine that contains potentially all lymphoma-derived antigens. This cross-sectional study enrolled 2,776 participants in a comprehensive health management program which included measurement of fasting plasma glucose and HbA1c, along with screening colonoscopy. A novel antimicrobial peptide designated melectin was isolated from the venom of the cleptoparasitic bee Melecta albifrons.

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Exposing these conidia to fresh apple juice increased conidial germination to the level comparable to that exhibited by conidia which were not exposed to the antagonist. The overall end-scores for individual residents were announced periodically to the full surgical department, and the winner was awarded a prize. In lesions induced by the latter there was relatively little accompanying anoxal degeneration and subsequent remyelination was prominent. In another experiment female rats were exposed to cadmium oxide at a concentration of 0.02 mg Cd/m3 or 0.16 mg Cd/m3 for 5 hours a day and 5 days weekly for a period of 5 months or 1 mg Cd/m3 for 4 months.

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GPs are inadequately equipped to manage growing demand for cancer care, study warns. During disease, the flow of blood cells through the capillary network is one of the most perilous events in the microcirculation.

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Symptomatic presentation of a completely duplicated collecting system with upper-pole ectopic ureteral insertion is rare in the adult. Treatment with AM-251 also reduced the depletion of CGRP, suppressed Fos-induction, and prevented the increase in capsaicin-evoked spinal CGRP release. In the present study, CsA (5 mg/kg, subcutaneously) was administered to each animal just after, 2 and 6 h after ischemia so as not to exert its immunosuppressive effect.

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Parameterization of the temperature dependence of the Debye-Waller factors. We have also found that the plasma and the tumor tissues of these patients contains a potent non-gastrin secretagogue. Information from recent studies of 5-, 12- and 14-year old children, co-ordinated by the British Association for the Study of Community Dentistry (BASCD) was used. Of 386 results, 26 full texts were evaluated, leading to the inclusion of 18 articles (relating to 12 models). The rate of binary restenosis and the incidence of subacute stent thrombosis did not differ between both drug groups.

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Cathepsin B mediates caspase-independent cell death induced by microtubule stabilizing agents in non-small cell lung cancer cells. 5-demethylovalicin, as a methionine aminopeptidase-2 inhibitor produced by Chrysosporium.

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Self-efficacy and health status in patients with coronary heart disease: findings from the heart and soul study. The content of anthrasesamone F increased gradually with seed maturation and drastically on air-drying, the final stage in sesame cultivation. Although A-A embolism is the main stroke mechanism, local branch occlusion is another important stroke mechanism. The JRC GMO-Amplicons supports control laboratories in the design and assessment of GMO methods, providing inter-alia in silico prediction of primers specificity and GM targets coverage.

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Oxytocin-induced inhibition was present in cells responding to capsaicin, and when internal stores of calcium were depleted with thapsigargin. A new series of dopamine D4 receptor agonists, 1-aryl-3-(4-pyridinepiperazin-1-yl)propanone oximes, was designed through the modification of known dopamine D4 receptor agonist PD 168077. Further, it is argued that the nonlinear, adaptive mechanisms that produce the second-order kernel are involved in shaping the time course of the response. Plasma determination of homocysteine on CPC Immulite 2000: comparison with determination on IMX Abbott Male, Sprague-Dawley rats received L(5)/L(6) spinal nerve ligation (SNL).

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Effects of canrenoate on red cell sodium transport and calf flow in essential hypertension. Biomechanical evaluation of porous bioactive ceramics after implantation: micro CT-based three-dimensional finite element analysis. It affects many workers, is associated with high costs to industry and the individual, and can negatively influence the quality of life for the workers.

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Homologous recombination (HR) is an important conserved process for DNA repair and ensures maintenance of genome integrity. The results on objective testing indicated that the CFS patients had some mild memory impairment, but only on tasks requiring conceptually driven encoding and retrieval processes.

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Mutants in exc-7 form small cysts throughout the tubular excretory canals that regulate organismal osmolarity. In fact, higher GTP doses were requested to obtain dopamine inhibition, suggesting that different G proteins were involved in the coupling of these two receptors with adenylate cyclase. Stroke volume index increased marginally in infants but remained depressed in children after intubation.

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This study maneuver allowed us to complete a subsequent RCT in 225 children following severe traumatic brain injury. Our understanding of lung tissue mechanics is embodied in various mathematical models, that relate measurements of transpulmonary pressure to lung volume and flow. The therapeutical benefit of pentoxifylline (Trental) in vascular disorders and chronic diseases which provoke disturbances in nutritive microcirculation is reviewed. Alcohol consumption, diabetes, and coronary disease: An epidemiological perspective. There is no enough evidence to support the recommendation of methods to increase muscle tonus of upper airways in treatment of snoring.

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The prevalence of Th-2 cell-mediated conditions, such as atopy and atopic diseases, appeared to be lower in BD, a Th-1 cell-mediated disease. It was tested whether the amount of information that was received influenced the outcome of the discrete choice experiment. Carbon-bridged oligo(p-phenylenevinylene)s for photostable and broadly tunable, solution-processable thin film organic lasers. A significant limitation of his sharp vision remained in his other eye.

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Brief interventions have been studied with different populations of drinkers, with aims embracing both individual and population-level perspectives, and without well-specified contents. In particular, C9 acetylated sialic acids were mostly linked alpha 2-6 to beta-galactose.

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The timing of referral for pediatric cardiac care, however, was not related to ethnicity, median family income or household educational level. We report a new case of PCI occurring during the course of paraneoplastic dermatomyositis. It is proposed here that by introducing a dormant hold-out set of reflections, any problems with such bias can be avoided.

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All 16 women had persistent bleeding despite the maximal and optimal application of conservative measures. Sensitivity of hypogean and epigean freshwater copepods to agricultural pollutants. Knowing the most frequent types of primary varicosis and the principles of selective surgical treatment, the surgeon is able to perform a curative operation with a low complication rate and level of postoperative morbidity, high compliance, and excellent cosmetic results.

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Wild-type p53-producer derived cell lines exhibit an altered cell cycle, however. In recent years, with the regression of infectious diseases in developing countries, the focus has shifted more towards non communicable disorders.

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Design and therapeutic application of matrix metalloproteinase inhibitors. Consistent with these changes, loss of COX-2 resulted in the abolition or the significant delay of tumor onset when the cells were injected in the mammary fat pad of severe combined immunodeficient mice. Blood flow in tracheal mucosa/submucosa increased six times base line, but in tracheal smooth muscle the increase was only three times base line, and in cartilage it remained at base line. We compared childbirth-related outcomes for Medicaid recipients who received prenatal education and childbirth support from trained doulas with outcomes from a national sample of similar women and estimated potential cost savings. We propose to use optical low coherence reflectometry to measure the reflectance of both faces of a plane substrate with one side coated in antireflective layers.

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Therefore, the objectives of our solution are (1) providing a secure implementation of re-encryption in white-box attack contexts and (2) assuring the efficiency of the implementation even in multi-recipient cases. In some of the cases in the pneumonitis group, sICAM-1 levels began to increase at an early phase of irradiation. In the last years, many experimental studies performed in humans and in animals show the relationship between dietary fibre (DF) and lipemia. Physicians are sampled during the first stage, with 2 workdays per month subsampled from each physician in the second stage.

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Survey research in health education, as in other disciplines, attempts to provide estimates of population parameters from which inferences important to program delivery can be made. Our study shows that the transient fluoxetine-induced down-regulation of bdnf gene expression depends on an intact 5-hydroxytryptamine but not noradrenaline system or circulating glucocorticoids. Synthesis and multi-spectroscopic DNA binding study of 1,3,4-oxadiazole and 1,3,4-thiadiazole derivatives of fatty acid. Surface-associated antigens of second, third and fourth stage larvae of Dirofilaria immitis.

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All alpha1/alpha 5 chimeras containing alpha 5 NC1 residues 188-227 replicated the ability of alpha 5 NC1 to bind to alpha3NC1 and co-assemble into NC1 hexamers. To elucidate the potential roles of glucose transporter 1 (GLUT1) in human placenta during pregnancy, we examined the localization of GLUT1 in human placenta at various stages by immunohistochemistry with an anti-GLUT1 antibody by use of both light and electron microscopy. The rates of ultrasonic calling of males castrated as neonates were also decreased to female levels. MR-relaxometry might improve diagnostic reliability of magnetic resonance imaging for evaluation of cardiac involvement in systemic amyloidosis. Tests were conducted at quasi-static and dynamic rates of loading.

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On nicotine administration along with alcohol, an additive effect was observed in lipid peroxidation and the antioxidant defence mechanism. Association between week of the month and death from acute myocardial infarction in Washington state, 1988 to 1997. Effects of nitrogen dioxide and ozone on blood-borne cancer cell colonization of the lungs. Luminal narrowing was assessed in 238 transverse segments obtained from coronary arteries removed at postmortem. The thermodynamics of phase transitions in solids has been examined with allowance for the elastic energy of stresses arising owing to the difference in the densities of the initial and the forming phases.

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These data demonstrate selective induction of functional NIS in breast cancer by tRA. Surgical resection of biliary tract malignancies after interventional radiology treatment. The National Institute of Public Health - fifty years of activity and development in retrospect.

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An interpretation of focusing and image formation on scattering of electromagnetic waves by a dielectric cylinder (a cylindrical lens) is proposed on the basis of the full Maxwell theory. Intestinal inflammation and a systemic response to bacterial antigens can develop in the absence of a measurable disruption of intestinal permeability. Characterization of full-length neurofibromin: tubulin inhibits Ras GAP activity. Cut is a diverged homeobox gene that is essential for normal development of the Malpighian tubules in Drosophila melanogaster. We studied the response (disappearance of pain and functional improvement) to pamidronate (60 mg/day for 3 days) in 29 patients with RSD refractory to previous treatment for at least 14 days.

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These first subcellular localization studies indicate the presence of high levels of NGF in neurons not known to be sensitive to the trophic molecule. Penetrating injuries to the face: delayed versus primary treatment--considerations for delayed treatment. SYSTEMATIC LITERATURE REVIEW ON MODELS AND PRACTICES OF EARLY CHILDHOOD INTERVENTION IN BRAZIL.

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The degrading effects of two of the fluids were reversed by anti-interleukin-1 alpha (IL-1 alpha) while degradation by the third and fourth fluids were reversed by anti-interleukin-1 beta (IL-1 beta) and anti-tumour necrosis factor-alpha (TNF-alpha), respectively. Bronchoscopic treatments are less morbid treatment alternatives than surgery and surgical bronchoplasty, especially for patients suffering from COPD and who have poor cardiovascular status due to their smoking history. Voiding cystourethrography was used for detection and grading of VUR. Enrollment in high-deductible health plans (HDHPs) has greatly increased in recent years. Data of age, gender, ethnic background, sexual preference, intravenous drug use and a diagnosis of VD or HIV infection for persons attending the VD Outpatient Clinic of the Department of Dermato-Venereology of the Dijkzigt University Hospital in Rotterdam, the Netherlands, for the first time were compared for the years 1993 and 1998.

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Treatment of the differentiating myoblasts with inhibitors of matrix metalloproteinases (MMPs) revealed that MMP activity at the elongation stage is a critical prerequisite to complete the successive myoblast cell fusion. The same solution actually is valid for every path in the network. In 1998 the Swedish noncommercial public health service Infomedica opened an Ask the Doctor service on its Internet portal.

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TS-2 significantly down-regulated myosin 1E (Myo1E), which is involved in release of clathrin-coated pits from plasma membranes. The efficacy of high-resolution (1)H nuclear magnetic resonance ((1)H-NMR) spectroscopy-based metabonomics was studied in a model of rat liver toxicity. Leather tanning workers: chromosomal aberrations in peripheral lymphocytes and micronuclei in exfoliated cells in urine. Magnetization reversal process of Zn-bonded anisotropic Sm-Fe-N permanent magnets.

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17p11.2 and Xq28 duplication detected in a girl diagnosed with Potocki-Lupski syndrome. We studied polymorphisms of the ApoH gene by the polymerase chain reaction-single strand conformation polymorphism technique and DNA sequencing in 140 PICH patients and 100 healthy control subjects. To compare the chronic and acute effects of light cigarette and regular cigarette smoking on coronary flow velocity reserve (CFVR). Although antibiotics have long been known to have multiple effects on bacterial cells at low concentrations, it is only with the advent of genome transcription analyses that these activities have been studied in detail at the level of cell metabolism.

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Eighteen studies compared levels of IH in LGB populations, four described prevention programs, and one investigated IH using qualitative methods. A Caenorhabditis elegans insulin-like signaling pathway regulates development, metabolism, and longevity. Preparation of mesoporous alumina particles by spray pyrolysis and application to double bond migration of 2-butene.

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CCPS analogs also induced acute changes in the levels and composition of endogenous Cers (upregulation of C16-, C14-, and C18-Cers, and downregulation of C24:0- and C24:1-Cers). The right lymphatic drainage system (RDS) was basically longitudinal and multi-stationed. Effect of mass discontinuity in the Wigner theory of resonant-tunneling diodes.