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Questions are raised about appropriate referral and follow-up for some clients. Tissue hypoxia and ischemia lead to depolarization of neuronal membranes, alteration in cellular ion homeostasis and changes in energy metabolism. Cognitive decline and human (Homo sapiens) aging: an investigation using a comparative neuropsychological approach.

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Catheter ablation of multiple ventricular tachycardias after myocardial infarction guided by combined contact and noncontact mapping. Malondialdehyde-acetaldehyde-protein adducts increase secretion of chemokines by rat hepatic stellate cells. There is great promise that machine learning methods combined with resting state functional MR imaging will aid in diagnosis of disease and guide potential treatment for conditions thought to be impossible to identify based on imaging alone, such as psychiatric disorders.

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According to the obtained results, the presence of LAS, NPEO and DEHP even at higher concentrations was not inhibitory to the bioprocess. Clinical significance of small airway obstruction markers in patients with asthma. Organic catatonic disorder--on the occurrence of a catatonic syndrome in a patient with encephalomyelitis disseminata Asymmetric Cerebrovascular Collateral Supply Affects Cognition in Patients with Unilateral Carotid Artery Stenosis.

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The disease is characterised by foci of demyelinisation with atypical astrocytes and oligodendrocytes. Rate of nucleotide synthesis in Saccharomyces cerevisiae at various growth phases Its stained glass windows and many busts of distinguished figures in the history of medicine are a constant reminder of the history of medicine.

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Evaluation of chest ultrasound integrated teaching of respiratory system physiology to medical students. Interleukin-1 (IL-1) and tumor necrosis factor alpha (TNF alpha) stimulated LIF production by chondrocyte monolayers and cartilage. One hundred and sixty-seven members replied to the letter, and 120 individuals from 22 countries completed the questionnaire (corresponding to approximately two-thirds of the clinical members of the ETA). Benefits and dangers connected with clinical use of microelements

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These cytotoxic T cells bear the alpha beta T cell receptor and recognize major histocompatibility complex class I antigens. There have been prevailed herpetic keratopathies (12 cases), edemato-bullous keratopathies--aphakic and pseudophakic (12 cases), followed by recurrent corneal erosions (4 cases), full thickness corneal and corneoscleral lacerations (4 cases) and alkali chemical corneo-conjunctival burns of II-nd/III-rd degree and III-rd degree. After a thorough review of the literature we further define and classify scapular dislocations to better understand prognosis and patient education. These findings suggest that serum Cyst C may be considered as a sensitive predictive parameter for reduced GFR. Some of these endogenous retroviruses can be pathogenic in mice and possibly in other animal species.

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Quantum statistics of polarized photoluminescence in ordered GaInP2. Deformed wing virus associated with Tropilaelaps mercedesae infesting European honey bees (Apis mellifera). Accidental injection of tranexamic acid (Transamin) during spinal anesthesia

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Twenty-two acinic cell carcinomas (ACC) occurred in the parotid gland. The magnetization transfer characteristics of human breast tissues: an in vitro NMR study. Both produce imagistic gestures along with more categorical signs or words. Three-dimensional growth and differentiation of ovarian tumor cell line in high aspect rotating-wall vessel: morphologic and embryologic considerations.

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A phase I trial of docetaxel and pulse-dose 17-allylamino-17-demethoxygeldanamycin in adult patients with solid tumors. This investigation compared several procedures for the pretreatment of formalin-fixed and paraffin-embedded tissue sections before their immunohistochemical staining. In the present studies, normal Sprague-Dawley and growth hormone (GH)-deficient (dw/dw) rats were administered the myotoxin, notexin, in the right M. Alternative models for the study of embryo-maternal cross-talk and signaling molecules from fertilisation to implantation.

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Possibility of evaluation of chest pain at the time of hospitalization Proinsulin was quantified by ELISA and characterized by mass spectrometry. The endothelial c-fos/c-jun mRNA expression were also detected by RT-PCR after treatment of triptolide. A new concept, unnested analysis of variance for stratified sampling and the use of computer-based methods for statistical analysis (the bootstrap method) and optimizing experimental design (nonlinear minimization procedure) are described in this report. The present study provides evidence that atorvastatin may be a potential therapeutic reagent for the treatment of lung fibrosis.

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Hemispheric differences in the voluntary inhibition of movement. Lanthanum was without effect on cromakalim-induced efflux whilst high concentrations of nifedipine were required to produce a significant inhibitory effect. Higher cortisol predicts less improvement in verbal memory performance after cardiac rehabilitation in patients with coronary artery disease. Fusion barrier distributions for heavy ion systems involving prolate and oblate target nuclei. A comparison of the organization of the supraoperon genes in other organisms represented in the database revealed unmistakable conservation of the linkage of these genes across wide phylogenetic boundaries, albeit with considerable gene shuffling.

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At 24-month follow-up, the patient showed no signs of infection and demonstrated a stable fusion mass. The prediction of relative solvent accessibility gives helpful information for the prediction of tertiary structure of a protein. Nitroglycerin produced dilatation of the basilar artery that was similar in sedentary and exercised nondiabetic and diabetic rats. Furthermore, deletional mapping of exon 6B identified sequences required for expression of exon 6B in RCS cells and these may correspond to purine-rich (ESE) and AC-rich (ACE) exonic splicing enhancers. The postmortem concentration of ZPT in heart blood was 0.68 microg/ml.

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Group 1 consisted of 81 patients without suspected pharyngeal or esophageal disease who demonstrated what was considered to be normal anatomy on all radiographic views. Methacholine induces wheal-and-flare reactions in human skin but does not release histamine in vivo as assessed by the skin microdialysis technique. Multivariable logistic models were fitted to examine the effects of pain management and demographic and clinical factors on change in pain severity.

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The presence of the gamma-carboxyglutamic acid domain in factor VIIa appears to facilitate the interaction with the negatively charged, amino-proximate site, whereas crosslinking of TF with VIIa or des-(1-38)-VIIa at the positively charged carboxyl-proximate site was similar. In recent years, the molecular structures of Ngb with carbon monoxide bound to the heme iron and without an exogenous ligand have been solved, and interesting structural changes have been noticed upon ligand binding. epidermidis supernatants resulted in increased IL-8 and GRO-alpha expression which could be suppressed by the serine protease inhibitor AEBSF and the NF-kappaB inhibitor BAY 11 but not by the cysteine protease inhibitor E64. This attitude has deprived psychology of a rich source of empirical observations, intriguing, testable hypotheses, and ingenious techniques of treatment. The significance of these observations to our understanding of domain interactions in molecular machines is discussed.

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Metformin increases blood flow and forearm glucose uptake in a group of non-obese type 2 diabetes patients. A total of 1,009 adults (516 men and 493 women) were interviewed in person throughout Manhattan. Studies on enzyme concentration and adaptation in human liver and adipose tissue. Platelet and leukocyte adhesion to endothelial cells in both unstimulated and posthypoxic betaS mice were significantly elevated over WT levels. Purulent acute otogenic meningitis complicated with thromboplebitis of the sinus cavernosus

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The Aboriginal population of Canada is at increased risk of exposure to the hepatitis C virus (HCV). A fraction of plasma transthyretin (TTR) circulates in HDL through binding to apolipoprotein A-I (apoA-I). Contribution of small vessel tone to the regulation of blood volume and formation of oedema. A biosensor-based characterization of the affinity maturation of the immune response against interferon-beta and correlations with neutralizing antibodies in treated multiple sclerosis patients.

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Human parathyroid grafts survived and functioned in mice treated with anti-CD4 monoclonal antibody. After 3 days, no increase in vitellus diameter was recorded from fibroblast-coupled oocytes maintained in culture medium or in the presence of media conditioned by 0.3 x 10(6) ml-1 Sertoli cells. Surprisingly, in a chronic GVHD model, the similar treatment with anti-CTLA-4 mAb significantly reduced serum IgE and IL-4 expression and ameliorated the manifestation of chronic GVHD. Many of them contain excessively high doses of caffeine along with a variety of stimulant compounds that have multiple effects in different parts of the human body. To characterize membrane receptors for LPS, solubilized membranes of human erythrocytes were subjected to affinity chromatography with an affinity adsorbent prepared by coupling S.

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Interpretation and prediction of inhaled drug particle accumulation in the lung and its associated toxicity. Despite lower pre-operative total leucocyte (WBC) and PMN counts found in this study, the total leucocyte and PMN response to surgical trauma in the Nigerian Negro is similar to previous observations made in the Caucasian. Parameter identification and sedative sensitivity analysis of an agitation-sedation model.

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To examine the role of dectin-1 in recognition of 1,3-beta-glucans and subsequent activation of intracellular signaling, the molecular characteristics of a carbohydrate recognition domain (CRD) of dectin-1 were investigated. Elevated intracranial pressure associated with hypermetabolism in isolated head trauma.

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Calcitonin gene-related peptide was able to eliminate sinus standstill and ventricular fibrillation resulting from administration of desacetyldigilanide-C. Conversely, when the inner monolayer area is expanded by the transport of DOPG from the outer monolayer to the inner monolayer of non-invaginated LUVs, a reversion to invaginated structures is observed. We then use a genetic algorithm to produce an optimal protein composed of peptides from this list properly ordered for cleavage.

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If the objective of intervention, to reduce mortality, is to be achieved, the population over the age of 5 cannot be ignored. GST-VCIP-RGD, but not GST-VCIP-RGE, specifically interacted with a subset of integrins, and these interactions were effectively blocked by anti-alpha(v)beta(3) and anti-alpha(5)beta(1) integrin antibodies, and by PAP2b/VCIP-derived peptides. A case of pseudoxanthoma elasticum with proliferative diabetic retinopathy. The prp2 gene of fission yeast has previously been shown to encode the large subunit of the splicing factor spU2AF.

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The results show that the slope of surface tension-concentration curves of sulfate salts depends to some extent upon cations while that of alkali metal nitrate gives almost the same magnitude. Recommendations for the treatment of emergency department (ED) patients with asymptomatic severely elevated blood pressure advise assessment for occult, acute hypertensive target-organ damage.

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Robot-assisted laparoscopic prostatectomy (RALP) has gained immense popularity. Treatment of advanced head and neck cancer by means of radiation therapy plus chemotherapy--a randomised trial. Cardiovascular changes associated with dehydration and drinking in unrestrained, lactating goats. Clinical trials show that asthma can be controlled in the majority of patients, but poorly controlled asthma still imposes a considerable burden. Recent research in patients with advanced cancer indicates that emotional distress appears to be caused by low levels of positive effect.

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The findings suggest that people may be able to self-identify generalised anxiety more accurately than depression based on a description of a prototypical case. Neutron diffraction studies showed that in the virus most of the coat protein consists of two alpha-helical segments arranged end-to-end with an intervening mobile surface loop. Microinjection of the D(2)-like (D(2)/D(3)) dopamine receptor agonist quinpirole (0.1-2.0 microg), but not D(1)-like (D(1)/D(5)) receptor agonist SKF-38393 (1.0, 5.0 microg), into VLO produced dose-dependent antinociception which was antagonized by the D(2)-like (D(2)/D(3)) receptor antagonist raclopride (1.5 microg).

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Clinical course, along with endoscopic, radiologic, and manometric esophageal studies, was reviewed. Lowest-order vertex corrections to the energy gap in covalent semiconductors. The distribution, isolation, spectral and oxygen-binding properties, stability of ferrous state (autoxidation), amino acid sequence and gene structure of indoleamine 2,3-dioxygenase (IDO)-like myoglobins are summarized, and their evolution is discussed. Sequential emergence of ABL-kinase mutations with loss of unmutated BCR-ABL allele during targeted therapies of CML.

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Cystic hygroma is a benign congenital lymphatic malformation affecting mainly the head and neck region in children. True collaboration among large federal agencies is rare, as is that among large and influential national foundations. The zebrafish is an established model of vertebrate development and is also receiving increasing attention in terms of human disease modelling.

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Although the catalytic triad of glutathione peroxidase (GPx) has been well recognized, there was little evidence for the relevance of the interactions among the triad amino acid residues, i.e., selenocysteine (U), glutamine (Q), and tryptophan (W), to the GPx antioxidative functions. Results from the present study are consistent with the current belief that implantation at a younger age provides greater benefit. The interplay between neurologic and immune systems may help to uncover the pathophysiologies of certain neuropsychiatric systems. Physical activity classification levels were derived from accelerometry and from the Health Survey for England physical activity interview, together with the number of episodes in which participants were moderately active for 30 min or more.

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We also examined the effects of intranasal exposure of CSE plus ovalbumin (OVA) on T(H)2-type immune responses and lung pathology. To determine if tin plating can be recommended for intraoral repair of ceramic veneered cast restorations where metal of unknown composition is exposed by loss of ceramic. A correlational and factor analysis and the effects of ovarian hormones. Evaluation of the Anti-Inflammatory, Antioxidant and Immunomodulatory Effects of the Organic Extract of the Red Sea Marine Sponge Xestospongia testudinaria against Carrageenan Induced Rat Paw Inflammation. Transmission of human African trypanosomiasis in the Komo-Mondah focus, Gabon.

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In conclusion, striatal interneurons immunoreactive for somatostatin, parvalbumin and choline acetyltransferase, but not those containing calretinin, receive strong inputs from the centromedian nucleus in monkeys. Most examples of intercontinental dispersal events after the Miocene contact between Africa and Asia involve mammal lineages. Proteasome inhibitor bortezomib has been shown to result in enhanced cytotoxicity and apoptosis when used alone or in combination with gemcitabine in pancreatic cancer cell lines. Ang II increased protein synthesis while PDGF-BB induced both DNA and protein synthesis.