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The role of the corporate sector, the influence of conflicts, and the value of classical mitigation measures (such as health impact assessments) are further examined. With gestations in the range 28-31 weeks, there was no significant change in neonatal death or CLD, but there was a significant reduction in incidence of pneumothorax (adjusted odds ratio 0.32).

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A study in 8 comatose intubated patients showed that the application site had to be adapted to the state of the patients treated, as salivary miconazole concentrations comparable to those observed with the gingival tablet in healthy volunteers, were obtained after application to the cheek. Predicted strain coverage of a meningococcal multicomponent vaccine (4CMenB) in Europe: a qualitative and quantitative assessment.

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Sperm-associated antigen-17 gene is essential for motile cilia function and neonatal survival. The targets of the differentially expressed miRNAs were predicted by Target Scan, miRBD, and DIANA-microT-CDS, and the results were analyzed by gene ontology (GO) and KEGG pathway analysis using FunNet. Silymarin, the antioxidant component of Silybum marianum, protects against burn-induced oxidative skin injury.

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By comparing the renal structures of the skate with those of dogfish, a unique type of circulation--as related to nephron segments, renal zones, and fine structure of the wall of the vessels--is revealed in marine elasmobranchs of different evolutionary levels. This qualitative explorative hypothesis-generating study is based on text analysis of the laws, regulations and guidelines, and qualitative interviews of informants representing all the organisational elements of the DP systems in both countries.

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A dose of 40 mg/m(2) of S-1 was administered orally twice daily for 7 days (80 mg/m(2)/day) preoperatively in ten patients with resectable gastric cancer, and the same dose of S-1 was administered for 28 consecutive days after gastrectomy. A comparative analysis of the morphology of the supramolecular complexes and the peculiarities of the molecular structure of triterpene glycosides studied, demonstrated that the structure of supramolecular complexes formed depends on the branching and length of the glycoside carbohydrate chain.

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Determination of D-sorbitol in human erythrocytes by an enzymatic fluorometric method with an improved deproteinization procedure. The intercellular adhesion molecule-1 (ICAM-1) and leptin are important inflammatory biomarkers. We speculate that miaD causes a decrease in ms2i6A-37 tRNA demodification or an increase in miaA gene expression but not at the level of operon transcription. Elemental iodine is produced on an industrial scale and has found a wide range of applications in innovative materials, including semiconductors--in particular, in solar cells.

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To study the endocrinologic and metabolic effects of metformin in combination with compound cyproterone acetate (CPA) on patients with polycystic ovarian syndrome (PCOS). women with type 1 diabetes experienced significant hardship during their pregnancy, including a higher incidence of hypoglycaemic episodes, a loss of hypoglycaemic symptom recognition and weight gain. Obtained data were analyzed by multiple regression analysis (MLR). Constitutive expression of CYP51 in the resistant strains was about 100-fold higher than that in the sensitive strains.

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Urinary desmosine excretion as a marker of lung injury in the adult respiratory distress syndrome. Stem cells have evoked considerable excitement in the animal-owning public because of the promise that stem cell technology could deliver tissue regeneration for injuries for which natural repair mechanisms do not deliver functional recovery and for which current therapeutic strategies have minimal effectiveness. While pharmacologic cardioprotection has proved to effectively reduce infarct size in the experimental models its clinical usefulness is problematic. Aluminum induces cross-resistance of potato to Phytophthora infestans.

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After seven months, the patient reappeared with systemic multiple metastases, with the exception of previous metastases that were enlarging significantly. GRP78 levels are highest in the heart during early organogenesis and levels decrease significantly by the fetal period. Making hospitals safer for older adults: updating quality metrics by understanding hospital-acquired delirium and its link to falls. Staining with JC-1 could predict resistance to both drugs, but did not allow distinction between sensitive dose-dependent strains (S-DD) or intermediate (I) resistance to Flu or 5-FC, respectively, from S strains.

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(Cyanomethylene)trimethylphosphorane (CMMP) mediates Mitsunobu-type reactions, which are a versatile method for the alkylation of various nucleophiles (HA) with alcohols (ROH) to give RA. Progressive androgen-independent prostate cancer with low serum PSA is characterized by visceral metastases, high proportion of lytic bone disease, sensitivity to cisplatin-based chemotherapy, and histological features of small cell or poorly differentiated prostate cancer. They provide flexible and convenient dosage forms for pediatric patients. Hyperimmunized rabbit anti-rat apolipoprotein antibodies showed reactivity to proteins in Saccharomyces cerevisiae.

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Although serum inhibin A concentrations are more accurate than hCG levels for predicting preclinical abortion after IVF, they had no advantage in forecasting ongoing or multiple ongoing pregnancies, suggesting that routine assessment of serum inhibin A concentrations during follow-up of IVF pregnancies is unjustified. The number of anterior horn neurons was counted using Nissl, ChAT and AChE staining. This retrospective study was conducted to analyze the clinical characteristics of early newborns with abdominal distention, aiming at identifying the underlying etiologic factors. In vitro analysis shows that Kis antitoxin, but not the Kid toxin, is cleaved specifically by the ClpAP protease.

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Asymmetry of chest diameter related to concomitant excavatum-type deformity is less likely to respond to bracing attempts. Selection is also highly important in influencing the population of all hospital clinics dealing with chronic nonfatal illness. The patients were screened for coagulation factor abnormalities to find out whether known prothrombotic risk factors could explain the high frequency of thromboembolism.

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A MEDLINE search (2000 to April 2017) was conducted using the terms hyperuricemia, gout, URAT-1, URAT-1 transporter, and lesinurad. The influence of work- and illness-related factors varies considerably between the early and late phases of recovery after breast cancer treatment. Here we describe a multi-copy selection system based on ade1 and ade2 auxotrophic parent strains and the respective attenuated markers with truncated promoter regions. BAD1, an adhesin and immune modulator of Blastomyces dermatitidis, is an essential virulence factor that is released extracellularly before association with the yeast surface.

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11C-acetate PET imaging of prostate cancer: detection of recurrent disease at PSA relapse. The concept of an organic cause of urinary retention in otherwise healthy young women has considerable importance in terms of correct management. Promising new cell types and the rapidly evolving concept of adult stem and progenitor cell fate may enable us to move towards regenerating viable and functional myocardium.

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Selection of marrow donors for patients lacking an HLA-identical sibling. Clinical trials were eligible for the current analysis if they enrolled patients with an MI more than 40 days prior to randomization to primary prevention ICD therapy vs usual care: Multicenter Automatic Defibrillator Implantation Trial I, Multicenter UnSustained Tachyardia Trial, Multicenter Automatic Defibrillator Implantation Trial II, and Sudden Cardiac Death in Heart Failure Trial. Our results confirmed that gene expression profiling in blood represents a relevant molecular phenotype to refine ITs in pig and to identify potential biomarkers that can provide new insights into immune response analysis.

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Detection of rubella virus immunoglobulin G (IgG) and IgM antibodies in whole blood on Whatman paper: comparison with detection in sera. At the end of the third course, the total mean score on the practical was 3.5 (range, 1.5-5.0). Classically, high signal-intensity in T2weighted (T2w) images identifies low-grade tumours, while anaplasia is characterized by T2 hypointensity. In order to determine the minimal toxic dose of a 5-day infusion of 5-fluorouracil (5--FU) in combination with an infusion of thymidine (TdR), 12 patients, received TdR at a dose of 8 g/m2/day for 5 1/2 days, beginning at the same time as a 5-day infusion of 5-FU at doses of 5--20 mg/kg/day.

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Impact-induced pressure gradients along three orthogonal axes in the human skull. Non-specific intravenous immunoglobulins in severe infections caused by Staphylococcus and group A Streptococcus

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This model corrects the standard diffusion approximation over all source-detector separation distances provided the beam is sufficiently wide compared to the scattering mean free path. The retinal pigment epithelium in minimally affected regions of the retina showed an increased proportion of the melanin complement of the cell within complex granules. On the mechanism of action of nicotinic acid in lowering serum lipids.

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Molecular oncology: from basic research towards clinical application. Administration of nitecapone to diabetic rats normalized urinary sodium excretion in a manner consistent with the dopamine-dependent inhibition of proximal tubule Na,K-ATPase activity. Abnormal proliferative response of the carotid artery of spontaneously hypertensive rats after angioplasty may be related to the depolarized state of its smooth muscle cells. Compared with native crotoxin, aggregates appear less myotoxic, are largely devoid of phospholipase activity, and are virtually non-toxic in mice.

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In other inflammatory diseases, the role of rituximab in auto immune bullous diseases and of omalizumab in chronic urticaria is better known. Electrocatalytic oxidation of NADH at the self-assembled monolayer of nickel(II) macrocycle on gold electrode. Studies were categorized into four groups based upon the endpoint analyzed, including biochemical control (BC), local control (LC), pathologic control (PC), and cause-specific survival (CSS). From analysis of scatter diagrams, we estimated axonal growth rate of alpha, beta, and non-alpha/beta cells as 1.4, 1.1, 1.0 mm/day, respectively.

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It is suggested that the paired pleural cells might be involved in the neuronal mechanism for co-ordination of defensive withdrawal with inhibition of feeding. We conclude that TIE is required during embryonic development for the integrity and survival of vascular endothelial cells, particularly in the regions undergoing angiogenic growth of capillaries. In endometrial carcinoma cells, the production of progesterone also increased with over-expression of StAR and the F2 system.

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Effects of inhibitors of protein synthesis on lysis of Escherichia coli induced by beta-lactam antibiotics. Adenovirus inclusions were identified by light microscopy in the kidneys only. Unilateral hydrocephalus caused by occlusion of the foramen of Monro is rare. The basis for the greater HSK lesion susceptibility of CXCR2-/- mice was associated with an elevated IL-6 response, which appeared in turn to induce the angiogenic factor, vascular endothelial growth factor.

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A trans-Golgi network retention signal YQRL fused to ricin A chain significantly enhances its cytotoxicity. The in vivo blood, fat and muscle concentrations of lignocaine and bupivacaine in the hindquarters of sheep. Fifteen items and four total scores were significantly higher in the older group.

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In spite of careful technique in placement of an epidural catheter, the test dose of 3 ml bupivacaine 0.5 per cent produced an unusual block which ascended to include sensory blockade of the fifth cranial nerve, but the motor components of the cervical and thoracic segments were spared. There are few long-term data on which to base decisions of management in pregnancy. This toxin links itself to the receptors of the axon membrane of the motor neurons, preventing the release of acetylcholine in the neuromuscular junction, causing flaccid paralysis of the cranial nerves and skeleton musculature.

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Cadmium-induced changes in luminal fluid pH in testis and epididymis of the rat in vivo. A CGA----TGA mutation at codon 111 in exon 3 of the phenylalanine hydroxylase (PAH) gene was recently identified in a Chinese phenylketonuria (PKU) patient. Pressure to provide value will require providers, insurers, and purchasers to cooperate and coordinate health care services. In contrast, the regulation of pel expression by temperature or nitrogen starvation, observed in Er.

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Small and rural communities face unique challenges in improving healthcare quality. Furthermore, the results demonstrated a specific spatiotemporal shift from central to frontal areas between N1P2 and LN that was pronounced in dichotic trials. A database homology search using the BLASTp algorithm showed the highest similarity to a serine proteinase from Fusarium sporotrichioides. Our initial report on mice lacking caveolin-1 (Cav-1) demonstrated a loss of caveolae and perturbations in endothelial cell function.

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The objective was to evaluate the safety and effectiveness of soft-tissue augmentation of calcium hydroxylapatite (Radiesse) in patients with facial lipoatrophy secondary to human immunodeficiency virus disease. However, these trials and other analyses indicate a difference in time distribution of stent thrombosis, with more cases of stent thrombosis occurring later (ie, after 1 year) in patients with DES--a problem to which the lack of adequate antiplatelet therapy appears to be a main contributor.

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The role of CD40/CD40 ligand interactions in bone marrow granulopoiesis. Addition of these two agents into standard hyperpotassium cardioplegic solution increased twice the recovery of the aortic output and improved restoration of volume work and an index of functional recovery. The purpose of this study was to assess the oestrogenic action of a chemically cured, no-mix (Rely-a-Bond) and a light-cured (Reliance) orthodontic adhesive resin. This indicates that TBT is passed on primarily via the water, while TPT is passed on to a larger extent via the sediment.

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After eliminating the masticatory muscles as a growth factor in our animal model is was possible to analyze the blood supply to the skull in sufficient detail. A spectrum of internal and external factors contributes to the disease promotion such as a genetic predisposition, chronic inflammatory processes, exposure to toxic compounds, abundant stress factors, a shift-worker job, etc. While beta(2)-agonists are often used for short-term relief of acute bronchospasm, anti-inflammatory agents are required for the long-term management of chronic inflammation in this disease.

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By rapidly migrating from one cell pole to the other, MinD helps to block unwanted septation events at the poles. This is the only case of epidural lipomatosis with an associated syrinx that we have seen reported in the world literature. Echocardiographic analysis of visibly healthy wild-type RhoA transgenic mice revealed no significant change in left ventricular function. DRCR.net-protocol refraction and EVA were measured before and after dilation in diabetic subjects by independent, masked examiners. Micronucleus levels were used as a quantitative indicator of chromosome damage in vivo.

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We report a case with thrombosis of the ascending aorta, aortic arch, brachiocephalic trunk and subclavian artery. All patients had dramatic improvement in symptoms within a few days and none has relapsed during follow-up. To evaluate the effect of different polishing time on microleakage of different resin composite restorations (Filtek Z350 and Filtek Z250).

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Development of streptococcal pyrogenic exotoxin C vaccine toxoids that are protective in the rabbit model of toxic shock syndrome. Preparation and antininflammatory properties of some 5-(2-anilinophenyl)tetrazoles. A 90-year-old woman was referred with features of a well-established small bowel obstruction (SBO).

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The relevant factors of the 135 patients with relapse were evaluated: sex, Osserman classification, age while being operated on, duration of preoperative period, pathologic type of thymus, use of steroid before operation, infection after operation, whether only taking anticholinesterase drugs after operation, use of steroid immediately after operation, stopping medicine or decreasing the dose of medicine within 1-3 months after remission of symptoms. Stronger immune responsiveness of blacks vs whites may account for renal allograft survival differences. The nature of the normalized variance reveals the basic relationship between the stochasticity and system size in gene expression. Role of purine-rich exonic splicing enhancers in nuclear retention of pre-mRNAs.

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The most abundant eCB in the central nervous system (CNS), 2-arachidonoyl glycerol (2-AG), triggers a broad range of signalling events by acting on CB1, the most abundant G protein-coupled receptor in the CNS. Two-photon polymerization technique was applied to generate three-dimensional (3D) scaffold-like structures using the photosensitive organic-inorganic hybrid polymer ORMOCER. Complications after percutaneous transluminal angioplasty and vascular surgery After 12 weeks, an intracardiac perfusion was performed to remove the thoracic spine and the spinal cord.

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This process is thought to be regulated by molecules that regulate synapse number, morphology and strength. The general flow patterns generated in the rigid AAA model were in agreement with the literature.

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CYP105A1 from Streptomyces griseolus has the capability of converting vitamin D 3 (VD 3) to its active form, 1alpha,25-dihydroxyvitamin D 3 (1alpha,25(OH) 2D 3) by a two-step hydroxylation reaction. It was not until Finsterer, in 1939, demonstrated the virtues of early operation that surgery began to take its place in the treatment of this condition, mainly by gastric resection. Transoesophageal Doppler compared to central venous pressure for perioperative hemodynamic monitoring and fluid guidance in liver resection.

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The herbicidal activity of alachlor applied as organoclay formulation was limited to the top soil whereas it disappeared from the top soil in plots treated with EC commercial formulation. Is permanent parasitism reversible?--critical evidence from early evolution of house dust mites. Ventilation was kept constant in the occlusive patients group (group OD).