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Tealep (Finasteride)

Tealep, a 5-alpha reductase inhibitor, widely used in the medical management of male pattern hairloss, has been reported to cause sexual side effects. This article critically examines the evidence available and makes recommendations as to how a physician should counsel a patient while prescribing the drug. The bioavailability of Tealep 1 mg following oral intake ranges from 26-170% with a mean of 65%. The average peak plasma concentration has been found to be 9.2 ng/ml measured 1-2 hours after administration. The bioavailability of Tealep is not related to food intake. Tealep is extensively metabolized in liver by Cytochrome P450 3A4 enzyme subfamily and excreted both in urine and feces. The terminal half-life is approximately 5-6 hours in men between 18-60 years of age and 8 hours in men more than 70 years of age.

Other names for this medication:
Finasteride, Androfin, Avertex, Daric, Fenered, Finahair, Finalo, Finalop, Finar, Finara, Finast, Finax, Fincar, Finpecia, Firide, Monast, Prohair, Propecia, Proscalpin, Proscar, Prosteride, Reduprost, Renacidin, Sutrico, Symasteride, Tealep, Tensen,

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Contact inhibition of A-PSMC combined with serum depletion and androgen deprivation down-regulated AR mRNA levels, and dihydrotestosterone (DHT) counteracted this effect. Three regions of interest with different background intensities but equal flow were examined. To assess the quality of care of acute myocardial infarction (AMI) in a rural health region. Structure and Function in the Lunge Feeding Apparatus: Mechanical Properties of the Fin Whale Mandible. Paclitaxel 80 mg/m2 was administered intravenously weekly on days 1 and 8.

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Rotavirus can be detected in the serum of mice and children and causes biliary atresia in neonatal mice. The lactulose-mannitol test was performed to assess gut permeability. PLT revealed changes in 27 (0.9), NBT-PABA-in 25 (0.83) and CH-in 22 (0.73) patients with acp. Here we show that astrocytes in culture exhibit basal P2X7R activity.

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These difficulties pose considerable obstacles when animal studies with M. Although recent studies have provided a wealth of detail regarding these mechanisms in the adult human brain, investigations are also being extended to nonhuman primates, to infants, and to patients with psychiatric disorders. The effects of LPS/IFN-gamma were reversed by ABLOO, and BL without acetyl side groups showed only a weak inhibitory action.

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Lyme Disease was confirmed by the characteristic erythema migrans rash and Lyme serologies. The foam is placed over the wound and the wound is covered with an adherent, occlusive dressing thus converting the open wound to a controlled closed wound. Using a passive cutaneous anaphylaxis (PCA) model, the antianaphylactic effects of EA were examined. In vivo characterization of murine myocardial perfusion with myocardial contrast echocardiography: validation and application in nitric oxide synthase 3 deficient mice. Changes in inositol 1,4,5-trisphosphate and inositol 1,3,4,5- tetrakisphosphate mass accumulations in cultured adrenal chromaffin cells in response to bradykinin and histamine.

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This report details the occurrences of genitourinary trauma experienced during Operation Iraqi Freedom at a United States Army Combat Support Hospital, and determines if wearing body armor decreases the frequency of genitourinary and specifically kidney trauma. Advances in this field have allowed us to begin to focus on issues related to quality of life such as fertility, conception, and pregnancy among women with vasculitis. Bone marrow production of erythrocytes in patients with pulmonary emphysema

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Moreover, when a plasmid containing a putative repeat element from UA96 (pPC264) was used as a probe, it hybridized to the same five EcoRI fragments in both T8 and UA96. A systematic review of the literature, as well as a search for abstracts presented to relevant peer-reviewed meetings, was performed.

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Diterpenoids, norditerpenoids, and secosteroids from the Formosan soft coral Cespitularia hypotentaculata. Altogether, these results suggest that prolactin may directly stimulate angiogenesis, which could be one of the mechanisms by which prolactin contributes to breast cancer progression, thereby providing a potential tool for intervention. It is concluded that NH3 and glutamine are essential for the stabilization and induction of glutaminase activity in hepatocytes. Real pre-recorded neuronal and simulated signals, as well as their power spectra, are compared in terms of the main conventional EEG frequency peaks. Understanding the status and developmental prospects of nanotechnology in USA and China is important for policy-makers to decide nanotechnology priorities and funding, and to explore new ways for global cooperation on key issues.

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The osseous mass growing was noted on implant surface and alveolar process thickening in the implantation zone under alveolar process as the influence of early functional loads. The patient had transient neurologic deterioration postoperatively that recovered to preoperative level within 2 weeks. The distribution of azidothymidine palmitate galactosylated liposomes in mice

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Large for gestational age infants born from nondiabetic mothers showed delayed fall in pulmonary arterial pressure similar to those born from diabetic mothers but showed lower proportion of septal hypertrophy. It can be expected that, beyond a certain threshold, negative effects ensued, leading to neuropathology and increased susceptibility for certain psychiatric disorders.

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The giant cells, which were the predominant cellular components of the blood-polymer interface layer, contained from a few to more that one hundred nuclei and varied in diameter up to 400 microns. Human saliva is an attractive body fluid for disease diagnosis and prognosis because saliva testing is simple, safe, low-cost and noninvasive. We attempted modelling of the transmembrane voltage Vm time course, induced by different applied voltage Vs waveforms, taking into account only the shapes and the relative Vs and Vm amplitudes. GRP78 was induced strongly both in interneurons and motor neurons at an early stage of reperfusion, but prolonged expression was observed only in interneurons. It is synergistic with platinum and radiation in preclinical models and has been tested clinically in every stage of NSCLC.

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Chemical modification, such as oxidation of low-density lipoproteins (LDL), is tightly associated with increased LDL uptake by macrophages and the development of arterial fatty streaks. We believe this newly discovered mechanism provides fundamental insight to guide the creation of new solar materials that exhibit high efficiencies through multiple charge generation. Gold Medal, Distinguished Contribution to Education in Psychology, Unique Contribution in the Teaching of Psychology, and the National Media (Ernest R. Apolipoprotein E exerts selective and differential control over vitamin E concentrations in different areas of mammalian brain. Enemy recognition is linked to soldier size in a polymorphic stingless bee.

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Despite of tremendous research efforts, however, molecular mechanisms on AR regulation remain poorly understood, particularly for castration resistant prostate cancer (CRPC). Over the past two decades there has been renewed interest in the use of color perimetry as a means of detecting early functional defects resulting from glaucomatous optic neuropathy and other forms of ophthalmic and neurologic pathology.

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Fully-automated approach for online dried blood spot extraction and bioanalysis by two-dimensional-liquid chromatography coupled with high-resolution quadrupole time-of-flight mass spectrometry. This coexistence, on the other hand, introduces a novel pathogenetic aspect of PXE and an important research challenge. To directly evaluate this hypothesis, cell suspensions, isolated from bronchoalveolar lavage fluid and from open lung biopsies of nonsmokers and cigarette smokers with normal lung parenchyma and from open lung biopsies of nonsmokers and cigarette smokers who have sarcoidosis were evaluated for the presence of neutrophils. The steroid receptor RNA activator (SRA) is a unique modulator of steroid receptor transcriptional activity, as it is able to mediate its coregulatory effects as a RNA molecule. Supply-side deficiencies in structural inputs and processes of delivering HIV testing and counselling during antenatal care indicate critical shortcomings in the quality of care provided.

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Microscopic theory of chain pullout in polymeric liquid crystals. Oral tocolytic therapy with clenbuterol--determination of the plasma level

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However, the mechanism(s) by which IFN-alpha/beta contribute to the NK-cell-mediated antiviral response is not well understood. Additionally, previous reports indicated that glycosylation of Asn-5 and Asn-75, the two potential sites of N-glycosylation in renin, is not necessary for the secretion of prorenin from mammalian cells. Cross-Sectional Predictors of Sexual Assault Perpetration in a Community Sample of Single African American and Caucasian Men.

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For this reason, the serratus anterior transplant is our flap of choice for the treatment of large palmar defects. NMDA neurotoxicity in murine cortical cell cultures is not attenuated by hemoglobin or inhibition of nitric oxide synthesis. In this review, we will consider whether CD200R signaling functions within a framework of paired activating and inhibitory receptors and whether the inhibitory signal delivered has functional consequences beyond inhibition of myeloid cell proinflammatory activation. Sex differences on the WMS-III: findings concerning verbal paired associates and faces.

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Longer travel distances were associated with decreased overall survival, especially in the 3rd quartile of our study. The effects of minimizing ambulance diversion hours on emergency departments.

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Using parathion-methyl as a model, after a simple hydrolyzation process, p-nitrophenol as the hydrolysate of parathion-methyl could be obtained, the fabricated derivative photoelectrochemical sensor showed good performances with a rapid response, instrument simple and portable, low detection limit (0.08 nmol L(-1)) at a signal-to-noise ratio of 3, and good selectivity against other pesticides and possible interferences. While depression and apathy are common after stroke, past studies have done little to examine the influence of these two symptoms on functional outcome respectively. Frequently, the ostomised patient is subjected to pharmacological therapy. The distinction between lymphoma-like lesion and lymphoma of uterine cervix depends primarily on the clinical and histopathologic features.

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On the role of exfoliative cytology in the detection of cancer of uterine cervix There were 297 patients who were found to have atherosclerotic abdominal aortic aneurysm (AAA).

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This novel theory enables the determination of factors dominating the transport in polymers and a comparison to tunneling without thermal fluctuations is also provided. Adenovirus vectors expressing Srebp-1c (also known as Srebf1) and small interfering RNA (siRNA) against Srebp-1c were transfected into the L6 cells. To evaluate the validity of a new protocol for Emergency Medicine in a large cohort of patients referred to in-hospital care. Far higher co-staining percentage of CD133/ Ki-67 in fibroblastic meningioma samples compared to meningothelial subtype, a histological meningioma variant, architectonically resembling the non-neoplastic meningeal cells, gave us the impression that CD133 may play a role in the formation and progression of fibroblastic meningioma variants.

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Uptake and degradation of filamentous actin and vitamin D-binding protein in the rat. In LLC-PK1 cells, the redistribution of PKC alpha, a predominant isoform of PKC detected, was studied utilizing western blotting after stimulation with vasopressin.

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Binding of the anti-cancer drug daunomycin to DNA probed by second harmonic generation. We have analysed all the pap smear performed during two periods.

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The result of author keywords analysis reveals that Molecular Dynamics, MEMS, Hard Disk and Diamond like Carbon are major research topics. Single myocytes were dissociated by enzymatic dissociation method.

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Understanding reasons for medication-taking behaviour during the journey through joint replacement may be helpful to health professionals. Motility data from patients were compared with those obtained in healthy control subjects.

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The purpose of this article is to review the types and presentations of BPF and to describe the role of noninvasive imaging for diagnosis and surgical treatment planning. Survival rates increased for nearly all types of cancer in children and adolescents. POS produced a somewhat longer-lasting efflux of 5-HT, as compared to IMS. The HH program was based on the World Health Organization 5 Moments for Hand Hygiene program, and included standardised educational materials and a regular audit system of HH compliance.

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However, an increase in the fluid pressure did not cause a statistically significant increase in the stiffness of the femoral head. In addition to fruit, the pathogen was isolated from blighted blossoms, water-soaked or necrotic leaf lesions, symptomless peduncles, and spurs and wood from branches showing dieback symptoms, indicating that the amount of tissue that may be infected is more extensive than previously considered. Conservative management of a chylothorax in a 57-year-old man was unsuccessful (25 l chylous fluid removed over three weeks). Seprase-dPPIV association and prolyl peptidase and gelatinase activities of the protease complex.

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We developed a novel adduct, GX-95, of silver with nanometer-scale particles to peptidic hydrolysates from collagen. Similarly to younger ones, also in older patients, diabetes does not negatively influence the safety, tolerability and efficacy of carvedilol.

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Platelet-rich thrombi are resistant to lysis by tissue plasminogen activator (tPA). This location factor concept has been used for monitoring the heat-induced translocation of ADH and location of penicillin acylase during the growth period of E. Comparison of visual sensitivity for suppression of pineal melatonin and circadian phase-shifting in the golden hamster. Compared with the males, females showed higher metabolism in the posterior part and lower metabolism in the anterior part of the brain. Phenomenology of anomalous self-experience in early schizophrenia.

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Folate linked one-carbon units are essential for DNA synthesis and repair and as a source of methyl groups for biological methylation reactions. The clustering of MS components may interact to synergistically affect arterial stiffness, even though the individual MS components, except for an elevated BP, do not affect arterial stiffness independently.

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Structure and expression of two highly related genes encoding SCM-1/human lymphotactin. Recently opioid receptors have been identified on peripheral processes of sensory neurons. The Third International Workshop on Drosophila Cell Division Cycle brought together researchers focusing on DNA replication, mitosis, meiosis, cell cycle regulation, checkpoints, asymmetric division, cell and tissue growth, and tumorgenesis. Development of multiple subcutaneous nodules in a patient with rheumatoid arthritis during methotrexate therapy In contrast, the disrupted lens (dsl) mutants are phenotypically normal until 5 dpf, and then undergo lens disorganization and cell degeneration that is apparent by 7 dpf.

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Furthermore, a number of animal studies have revealed the potential of bacteriophage for the control of various foodborne pathogens within the animal gastrointestinal tract and to subsequently decrease the likelihood of foodborne outbreaks. This indicates that calnexin may act in the quality control of glycoproteins. Furthermore, our data exhibited that levels of MIF, AMP-activated protein kinase activation, and autophagy were elevated concurrently in human failing hearts.

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Furthermore, we showed that all-trans retinoic acid down-regulated matrix metalloproteinase-9 expression in lymphocytes of untreated patients with early stage B chronic lymphocytic leukemia. Clinic employees reported varying success in improving awareness of blood donation in the broader community, in part because of varying employee engagement in community-wide activities and celebrations. The microtubule-associated protein tau forms a triple-stranded left-hand helical polymer. Emergence of extensive drug resistance (XDR) among Gram-negative bacilli in South Africa looms nearer. The tagged proteins were then digested with trypsin, and analyzed by Western blot analysis.

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The search for stable gas phase b(1) ions derived from aliphatic amino acids: a combined experimental and ab initio study. Multivariable analysis was used to identify factors associated with postoperative AKI, which was defined by risk, injury, failure, loss and end-stage (RIFLE) kidney disease criteria.

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Rhesus monkey and human share a similar topography of the corpus callosum as revealed by diffusion tensor MRI in vivo. Effects of recombinant erythropoietin on the concentration and cycling status of human marrow hematopoietic progenitor cells in vivo. Central achromatopsia is an impairment of color perception caused by damage to the visual association cortex. Linkage relationships of the apolipoprotein C1 gene and a cytochrome P450 gene (CYP2A) to myotonic dystrophy. Management consisted of a review of the literature, followed by educating her about the condition and close observation.

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Therefore, we developed a controlled simulated digestion system for testing different creatine derivatives in specific simulated parts of the human digestive system. From libraries of peptides and protein fragments, several inhibitors that block pheromone response in Saccharomyces cerevisiae have been isolated previously. The present report shows that the direct posterior surgical technique allows optimal exposure, reduction and internal fixation of medial split fractures of the tibial plateau with minimal trauma. The detrimental effect of the summer break on the progress of physical fitness was less in children who did participate in physical activity than in those who did not. Although various techniques have been used to monitor the viability of transferred tissues, there has been no technique designed specifically to check the flow within and the patency of the venous channel.

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Delivery system using polymers is an attractive alternative to colloidal carriers, in which hydrophobic drugs are chemically or physically loaded to polymers. Their results provide intriguing evidence for the involvement of two critical components of the MHC class II endosomal processing pathway, cathepsin S and the invariant chain, in the normal functioning of CD1. These findings suggest that the different variations of the SRN among various races should be concerned during the relevant procedures.

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Some problems in the administration of osmotic agents for intraocular pressure Fungal adaptation to the mammalian host: it is a new world, after all. The findings contribute to understanding the neurophysiology of ejaculation, and may be applicable to the evaluation of ejaculatory disorders. Videothoracoscopic thymectomy for nonthymomatous myasthenia gravis: results of 90 patients. Radical radiation therapy for prostate cancer in Japan: a Patterns of Care Study report.

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HDL modulates low-density lipoprotein and cell membrane oxidation through the action of paraoxonase-1 (PON1), which is one of the major mechanisms by which HDL is anti-atherogenic. In symptomatic localization-related epilepsy (SLRE)/simple partial seizures and SLRE/complex partial seizures, carbamazepine and oxcarbazepine were the respective treatments of choice, whereas in SLRE/secondarily generalized tonic-clonic seizures, carbamazepine, lamotrigine, and oxcarbazepine were treatments of choice. NO synthesis was quantitated by measuring both the ratio of citrulline and arginine (CIT/ARG-ratio) and total nitrite/nitrate (NOx) levels.

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The 11-amino acid human immunodeficiency virus TAT protein transduction domain is able to cross cell membranes and the blood-brain barrier, even when coupled amoclen cymbalta weight with larger peptides. Further, all the unrestricted multiple-group models provide an adequate fit to the data. Role of diffusion in the kinetics of reversible enzyme-catalyzed reactions.

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Recombinant interleukin-1 beta inhibits elastin formation by a neonatal rat lung fibroblast subtype. To determine ACE polymorphism in patients with HF secondary to Chagas disease achan oru malai undu kailasa temple india and patients with Chagas disease without systolic dysfunction, and to evaluate the relationship of the ACE polymorphism with different clinical variables.

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We speculate that the transcription of prostatic GSH-PO mRNA was regulated by testosterone or E2 and de novo synthesis of GSH-PO would thus be regulated at transcription level by testosterone or E2. In this review, the best characterized mechanisms that allow cancer cells to evade immune surveillance are overviewed and the most debated controversies constellating this complex field are highlighted. The aim of the present study was to examine whether intraperitoneal (i.p.) administration of selective mGluR5 antagonist 2-methyl-6-(phenylethynyl)-pyrydine (MPEP), injected prior to, peptazol 40 tablets immediately after or 30 min after training, affects acquisition and/or retrieval of the inhibitory step-down and active shuttle-box avoidance in rats. The culture system was used to test for enhancing effects of tick saliva and saliva components on A. There are no general methods for reliably assessing the firing properties or even calcium profiles of specific neurons in freely moving flies.

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Nearly 30 out of 48 loosened cups, retrieved 3 weeks to 11 years after implantation, were investigated. Cook-Medley hostility, anger, and the Type A behavior pattern quetapel quetiapine abuse in Finland. A case example is provided which illustrates each element of PEEDS-RAPEL

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In addition, hybrid conceptual processes for pre and post-combustion capture based on hydrate formation coupled mebendazole boots pharmacy with membrane separation are presented. The models developed using administrative data had consistently high predictive abilities for all models in both the derivation and validation subgroups.

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Abused adolescents reported lower family cohesion at baseline, although both abused and nonabused adolescents showed similar substance use reductions. In half of the slices investigated, HFS resulted in an initial increase of the evoked responses which decayed again after avorax tablet about 10 min.

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Treatment of rats with RU 38486 prevented the sepsis-induced increase in mRNA levels for MuRF1 and atrogin-1/MAFbx, suggesting that glucocorticoids participate in the upregulation of these genes in muscle during sepsis. Hearing impairment affects significant numbers of the people who are most likely to use healthcare services. The internally mixed phases are observed to adopt equilibrium geometries that are consistent with predictions based on surface energies and interfacial tensions and the volume fractions of the two immiscible phases. Despite the varied effects of HRT on inflammatory biomarkers, there is no definitive evidence that change in these markers results in modification of cardiovascular risk. Since the lifetimes of some important pollutants are long enough to be transported over buspirona genfar 5 mg long distance in the troposphere, regional control strategies for air pollution in downwind countries might be ineffective without considering the effects of long-range transport of pollutants from Asia.

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Few studies evaluate the risk of interaction with anticancer fexofenadine 180 chemist warehouse australia drugs in elderly patients suffering from cancer. Type A aortic dissection involving the carotid arteries: carotid stenting during open aortic arch surgery. (1976) conceptualization of self-concept structure and developmental processes that underlie self-concept formation.

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Glutathione-dependent bioactivation of gem-dihalomethanes and 1,2-, 1,3-, spironolakton pfizer careers and 1,4-dihaloalkanes leads to the formation of alpha-chlorosulfides, thiiranium ions, sulfenate esters, and tetrahydrothiophenium ions, respectively, and these reactions lead to reactive intermediate formation. For the first time the LDI and MALDI mass spectra of the highly chlorinated fullerene C(60)Cl(x)(x(max) approximately 32) are presented. Lumbar intervertebral body fusion cages: histological evaluation of clinically failed cages retrieved from humans. Disseminating multimedia protocols over Internet for emergency and catastrophe management.