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Topamac (Topiramate)

Topamac can be in combination with other drugs to treat partial-onset seizures, primary generalized tonic-clonic seizures, and seizures associated with Lennox-Gastaut syndrome (a severe form of childhood epilepsy). Topamac has both its approved and off-label uses. In the United States, the drug is officially approved by the U.S. Food and Drug Administration (FDA)

Other names for this medication:
Topiramate, Topamax, Epitomax, Letop, Neutop, Piramax, Talopam, Topamac, Topictal, Topigen, Topilex, Topimax, Topina, Topiramato, Topirol, Toplep,

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Phylogenetic analyses suggested that the Arabidopsis gene family contains at least two ancient classes of genes that diverged early in land plant evolution and may have separated vegetative from reproductive actins. Mortality by invasive meningococcal disease and related factors (organ dysfunction and multi-organ failure) were analysed. Obsessive-compulsive behavior spectrum: refining the research agenda for the DSM-V. This requirement, however, is usually not fulfilled in neuronal data.

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We believe he is the oldest patient who has had this operation successfully. When applied to image sequences, the 3-D Gabor representation displays spatiotemporal/spatiotemporal-frequency (st/stf) information, enabling the application of robust frequency domain methods with adjustable spatiotemporal resolution. This finding does not support the concept that professional drivers are resistant to sleep loss. Then radiotherapy was started using various methods, depending on the evidence of tumor dissemination.

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Fifteen years of imposex and tributyltin pollution monitoring along the Portuguese coast. These formulation issues include morphology of the complexes, lipids used, flexibility versus rigidity, colloidal suspension, overall charge, serum stability, half-life in circulation, biodistribution, delivery to and dissemination throughout target tissues. Cloud point formation based on mixed micelle in the presence of electrolyte for extraction, preconcentration, and spectrophotometric determination of trace amounts of hydrazine in water and biological samples. Event-related potentials were recorded from 11 subjects after ingesting caffeine (250 mg) or placebo. Members of the recently discovered SOCS/CIS/SSI family have been proposed as regulators of cytokine signaling, and while targets and mechanisms have been suggested for some family members, the precise role of these proteins remains to be defined.

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Toluene removal efficiencies and porosities calculated from this model correlated with the experimental data well. The literature on juvenile Parkinsonism in lupus has been reviewed.

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Interactions between immune activation cascades and biosynthesis of neurotransmitters. The aim of this study is to determine whether the NLR is a predictor of oncological outcomes in patients with stage I colorectal cancer who underwent curative surgery. We have used in situ hybridization to examine the spatial organization of cells expressing the early nodulin gene (ENOD2) during the development of alfalfa root nodules. FasL mRNA level was elevated and interaction of FasL with Fas receptor expressed in astrocytes may trigger cell death.

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Four groups of CDS rats fed a diabetogenic diet were treated with daily intraperitoneal injections of glycosphingolipids beta-glucosylceramide, beta-lactosylceramide, a combination of both (IGL), or vehicle (PBS) for up to 45 days. Longitudinal Gompertzian analysis of ischemic heart disease mortality in the U.S., 1962-1986: a method of demonstrating the deterministic dynamics describing its decline.

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Superheat-and-flush is one of the methods of disinfection used against Legionella in hospital water distribution systems. Widespread applications, however, are often limited by the lack of appropriately labeled, specific nucleic acid probes.

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For comparative purposes, we have studied the temporal evolution of the population activity in the superior parietal lobule (SPL) during the same reaching tasks and during a saccade task. Four different control strategies for stimulation amplitude are available. These studies revealed that cell communication within the mammalian ovarian follicle may involve transfer of bioactive material by microvesicles and exosomes.

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Blood ethanol and acetaldehyde levels were determined by gas chromatography after ethanol consumption. Mean non-instructed force was least when the thumb was the instructed digit, and increased progressively when the index, middle, ring, and little finger was the instructed digit. These phenomena contribute to the extinction of activation signals. The optimal treatment of ALF patients requires close collaboration among specialists in all of the involved clinical disciplines, as well as between peripheral hospitals and transplantation centers.

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Myelin, which is a multilamellar structure that sheathes the axon, is essential for normal neuronal function. Comparative effectiveness of intraperitoneal and intramuscular 3H-TDR injection routes in mice. Involvement of epigenetic mechanisms in the regulation of secreted phospholipase A2 expressions in Jurkat leukemia cells. This study shows a patient who presented with intermittent biliary tract obstruction caused by ampullary hamartoma.

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The cytosolic pool of GC-beta(1) was replenished after 48 h of continued cannabinoid drug treatment. The expression of the D6 decoy receptor in preeclamptic placentas was significantly lower than in normal placentas. These alterations lead to both a decrease in cellular proliferation and increased sensitivity to ROS. One of these patients with recurrent symptoms received an additional 30 Gy one year after initial treatment, making a total dose of 60 Gy. Some studies have suggested that certain types of metaplastic carcinoma have a more favorable prognosis as compared with others.

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A significant substantial agreement was observed between the final physician diagnoses and nurses using the Front Door Score. We recommend handheld POCT, airborne critical care testing, and disaster-specific mobile medical units in small-world networks worldwide. Many antibiotic regimens for treating Helicobacter pylori infection are currently used in clinical trials. Limited evidence exists on the effect of restorative material on the performance of a CAD-CAM system relative to marginal adaptation. The involvement of Pa marks an important evolution of the disease, well demonstrated in cystic fibrosis.

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Weight reduction is an essential first step in the management of obesity, hypertension, and kidney disease. From March 1989 to July 1990, Magnetic resonance imaging (MRI) examination was conducted in 60 patients with chronic injuries of the spine and the spinal cord, of whom 32 patients received exploration and decompression operation. This decrease was the result of the decreased incidence of cases in which an isolate had a PFGE pattern identical to that of an isolate from a faucet (7.0 cases per 1,000 admissions in 2000, vs 23.6 per 1,000 admissions in 1998) or from another patient (6.5 cases per 1,000 admissions in 2000 vs 16.5 cases per 1,000 admissions in 1998), whereas the incidence of cases in which the isolate had a unique PFGE pattern remained nearly unchanged (13.1 cases per 1,000 admissions in 2000 vs 15.6 cases per 1,000 admissions in 1998). Our data support the hypothesis that Mx1 expression protects mice against the high pathogenicity of H5N1 virus through inhibition of viral polymerase activity ultimately resulting in reduced viral growth and spread.

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Despite numerous studies there remained substantial gaps in the understanding of the control of renin release at the organ or cellular level. This review examines salivary constituents as potential diagnostic tests for periodontal disease. Accurately measured and properly heart-rate corrected QTc intervals show little daytime variability. On the other hand, statins, used for patients with hypercholesterolemia, have been shown to decrease the incidence of atherosclerosis-mediated diseases, but direct effects of statins on endothelial cells remain unclear.

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Linkage studies in man and experimental animals have defined multiple loci which regulate bone mass but the genes responsible for these effects remain to be defined. c-Src, c-Yes, and Lyn were activated at different levels in M phase, and the activation was inhibited by Cdc2 inactivation.

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Several technological advantages of STMs over conventional SSRs were also observed. The results show that PEC-60, like many other peptides, is expressed in the gastrointestinal tract and the central nervous system.

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Colonic ischemia following surgery for sigmoid colon and rectal cancer: a study of 10 cases and a review of the literature. At the crossroads of chemistry, biology, and materials: structural DNA nanotechnology.

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To prepare fluorescein sodium (FS) cationic liposomes and investigate the influence of cationic lipid (DC-chol) and polyethylene glycol (PEG) with different molecule weight (MW) on cationic liposome incorporation efficiency, cellular delivery and fluidity of liposome membrane. The symptoms of acquired nystagmus include blurred vision and oscillopsia. Census and interviews with mental health administrators and residential staff, the study identified siting patterns that linked housing affordability to development in mixed use, walkable neighborhoods that provided residents with access to community resources in a variety of small towns and metropolitan areas. The mean body weight was 84.7 per cent of usual body weight at discharge after PD plus NI and raised to 88.0 per cent at the hospital control (p less than 0.01) and to 93.7 per cent )p less than 0.05) after six months on pancrelipase ECM.

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Sonoelastography of the prostate: comparison with systematic biopsy findings in 492 patients. To investigate the anatomy of the brachial plexus, sciatic, and femoral nerves for the use of a peripheral nerve-stimulator to perform nerve blocks in dogs. The training included how to initiate the cardiac arrest call, how to use the AED, and how to start immediate resuscitation.

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The techniques implemented by the major vendors are briefly explained, including a comparison of the commonly used acronyms. Effects of chemotherapeutic agents on expression of somatostatin receptors in pancreatic tumor cells. Given the high prevalence of errors and the potential role consumers can play in identifying and preventing errors, there is a clear argument for increasing public awareness and understanding of issues relating to medication safety. In addition, the lowest fourth ventricular dose that significantly reduced food intake did not increase locomotor activity.

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CD19-redirected chimeric antigen receptor-modified T cells: a promising immunotherapy for children and adults with B-cell acute lymphoblastic leukemia (ALL). A case is presented in which the conventional radiograph was suggestive of avascular necrosis.

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A better understanding of the molecular nature of the ocular UPS function under normal and diabetic conditions is essential for development of novel strategies targeting its activity. Prolonged aortic cross-clamping in early infancy and method of myocardial preservation. We checked a panel of 20 cancer-associated genes (p14ARF, p16 CDKN2A, STAT-1, SOCS-1, DR-3, DR-6, PIG-7, BCL-2, H-TERT, BAX, EDNRB, DAPK, RASSF-1A, FADD, TMS-1, E-CADHERIN, ICAM-1, TIMP-3, MLH-1, COX-2) for DNA methylation. Follow-up imaging studies revealed a mass in the left hilar region extending into the pulmonary trunk and branches of the left pulmonary artery.

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In contrast, for the Ti-H implants the number of monocytes/macrophages decreased while the other cell populations remained constant. Maternal oxygen transport variables during the third trimester of normal pregnancy.

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These classes generally reflect specificity for a particular substrate. Abolition of the cyclic variations in radiosensitivity during meiosis in a sporulation mutant blocked in premeiotic DNA synthesis. Limited tissue distribution of the intestinal brush border myosin I protein. Application of Photofrin II as a specific radiosensitising agent in patients with bladder cancer--a report of two cases.

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Percentages, frequencies, mean, T-test, and variance analyses were computed for all study variables. In the inherited form, mutations in the prion protein gene are thought to cause the disease by altering the metabolism of the mutant PrP (PrP(M)) engendering its conversion into PrP(Sc).

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Pearson correlation and linear regression analysis was used to test the relationship between plain radiographical and magnetic resonance imaging Cobb measures. Immunocytes and different types of epidermal cells share cell surface antigen characteristics e.g. Possible synergistic effects between AGT and ACE gene polymorphism require further evaluation in a larger population.

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In the developing enteric nervous system of the moth Manduca sexta, an identified set of neurons (the EP cells) undergoes a stereotyped sequence of migration along the visceral muscle bands of the midgut prior to their differentiation. Transitional cell carcinoma of the renal pelvis in a long-term hemodialysis patient with autosomal dominant polycystic kidney. Roentgenologic features of lymphoid hyperplasia of the small intestine associated with dysgammaglobulinemia. Sclerokeratouveitis and lens dislocation in a patient with genital ulcer: was the great imitator imitated?

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Gastric analysis as a screening measure for cancer of the stomach. The significance of these innervation patterns is discussed in the light of structural information obtained from other vertebrate auditory receptors and in the light of available functional information derived from the turtle papilla. However, when alveolar hypoxia is global, as in diseases such as emphysema and cystic fibrosis, HPV leads to HPH (hypoxic pulmonary hypertension) and right heart failure. Electrolytes imbalance in saltwater near-drowning victims in the Gulf of Thailand.

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Some studies indicate, however, that the introduction of angiotensin-converting enzyme inhibitors for the treatment of cardiac failure is associated with transient weight gain and the development of oedema. Although the medication has marked therapeutic benefit for most patients, ther is considerable heterogeneity in drug response. The linearity range was found to be 5-50 microg/mL for the drug. Using these spectral analysis methods, the variations in the shape of the Doppler spectra as a function of time were presented in the form of sonograms in order to obtain medical information. Depression was positively correlated with increased severity of cognitive problems in both the CFS and control groups.

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Phosphorylated p38 was localized in small TNF-positive DRG neurons. Uneven distribution of aerobic mesophilic bacteria on human skin. On the importance of the bacterial flora in the reproduction of experimental ameobiasis Eight asymptomatic bacteriurias in girls (1.37 per cent) and eight in boys (1.19 per cent) were confirmed. Radiation alters the cargo of exosomes released from squamous head and neck cancer cells to promote migration of recipient cells.

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Designs were the same except that specific-pathogen-free (SPF) broiler eggs were used in Experiment 1 and commercial broiler eggs with maternal antibodies against reovirus were used in Experiment 2. Little is known about perceived risks associated with prenatal exposure to illicit drugs. Immersion vs pressure-breathing and diaphragmatic function in the upright position. After an ensuing short-term invasive mechanical ventilation and the administration of high dose glucocorticoids the patient was successfully extubated and the clinical status improved continuously.

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In the cerebellum, Purkinje and granule cell layers with the densest AMGBi were in folia adjacent to the fourth ventricle. The enzyme is ubiquitous in its organ distribution in mammals, but basal expression is relatively low in tissues other than the exocrine pancreas. These measurements provide detailed structural information, including molecular mass, length, base composition, complete nucleotide sequence, and confirmation of the sugar moieties and internucleotide linkages.

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In summary, the exotic geese facilitated both the local increase and the spatial spread of exotic grasses, which in turn provided the majority of their diet. The cDNA sequence of the murine proline/arginine-rich end leucine-rich repeat protein (PRELP) gene was cloned by PCR-based techniques. Further studies are needed to evaluate the diagnostic potential of MDCTA in specific subsets of the general entity of CVST such as cortical venous thrombosis, thrombosis of the cavernous sinus, and thrombosis of the internal cerebral veins. Alternatively, bacteria apply repressor-dependent mechanisms, in which transcription of heat shock genes is initiated from a classical housekeeping promoter and cis-acting DNA elements are used in concert with a cognate repressor protein to limit transcription under physiological conditions. The four plasmids tested, pACYC177, pACYC184, pSU2718, and pSU2719 were all able to establish in H.

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The threshold value is defined as the a priori probability for a GI diagnosis, where the benefit of endoscopy changes from unfavorable to favorable as the diagnostic probability increases. According to the retrospective self-reports, there were differences between the groups in fatigue, pain, and feeling of fever during the months preceding the crisis. Analysis of the apoenzyme active site reveals a potential deacylating water that was displaced by the inhibitor.

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Determination of sex from the proximal hand phalanges in a Thai population. Continuous monitoring of practices will reduce the risk for errors and support safe practices. Following delivery to the vacuole or lysosome, the cargo is degraded and the resulting macromolecules are released back into the cytosol for reuse. We briefly discuss the current views on the pathophysiology, diagnosis and management of this rare condition.

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Consumption of high carbohydrate, high fat, and normal chow is equally suppressed by a cannabinoid receptor antagonist in non-deprived rats. nilutamide vs bicalutamide Changing patterns of disease in Papua New Guinea over a period of 40 years from 1962. One has to remember that any systemic antibiotic treatment will be useful, clinically and microbiologically speaking, only when a mechanical therapy is also applied. Hydrophobic tips (i.e., polyester and polyethylene) show better detection sensitivity for polar compounds but not for non-polar compounds, while hydrophilic tips (wooden tips) show the opposite effect. Educating consumers in how to find and interpret Internet-based information on medicines may help them use their medicines in a safer and more-effective way.

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Erythromycin reduces the severity of bronchial hyperresponsiveness in asthma. The vulnerability of organ culture to microbial contamination can be turned into gabex plus tablets apple an advantage because it allows the detection of residual micro-organisms on the cornea before surgery. The postnatal development of the insertions of the medial collateral ligament in the rat knee.

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Relapsing hypocupraemic myelopathy requiring high-dose oral copper replacement. A study of 95 unaffected at-risk women and 95 partners was carried out using mailed, self-administered questionnaires nortrilen dragees 25 mg erfahrungsberichte iphone with validated measures of psychological outcome.

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Pediatric sleep-disordered breathing is known to negatively impact cognitive development. Tetraacetyl phytosphingosine-induced caspase activation and apoptosis occur through G2 arrest in human keratinocyte HaCaT cells. The vascular density within 100microm of the membranes was compared with that seen in normal tissue, and to that fluvin capsule corp surrounding the commercially available vascularizing membrane TheraCyte. Immunohistochemical localization of serotoninergic, enkephalinergic, and catecholaminergic cells in the brainstem and diencephalon of a cartilaginous fish, Hydrolagus colliei. Increased levels of pleiotrophin, a growth and differentiation factor that is active in various pathophysiologic processes, including angiogenesis, has been associated with osteoarthritic changes of human articular cartilage.

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Detection of immune cytoxan side effects forum complexes in human dental periapical lesions by anticomplement immunofluorescence technique. pylori increases epithelial cell proliferation and apoptosis in vivo, but that infection with bacteria of the cagA genotype leads to relatively more proliferation than apoptosis.

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Induction of skin lesions by ultraviolet B irradiation in a case of pemphigus erythematosus. We have obtained 5 specific DNA probes for African trypanosomes of the subgenera Trypanozoon and Nannomonas. This system uses radio frequency identification to automatically identify EME and increases the performance of the system allowing a large-scale supervision of EMEs. These and other techniques are reviewed, along with specific issues such as risks, benefits, drug dosage, and local anesthetic toxicity. Posttherapy surveillance of women probitor drug store with cervical cancer: an outcomes analysis.

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This study was designed to investigate the effect of HP oxactin antidepressants and alcohol on hepatocarcinoma HepG2 cells. Absorbed beta-carotene for the most part is converted, mainly into retinyl esters, but several details with respect to the cleavage reaction remain to be elucidated.

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Thus MDP, which is a pyrogenic molecule, is also able to release LP from rabbit phagocytes and to a lesser degree from human phagocytes, but does not cause gelation of limulus amebocyte lysate. Cytosolic proteins that consequently become conjugated to ubiquitin are targeted for degradation. Four of the patients regained a painless range of movement (30 to 50 degrees): two of these patients had gabapentin plus tablet uses a clinodactyly of 20 degrees. The effect of previous diet on plaque pH response to different foods.