Valosine is the first antidepressant that acts via inhibiting serotonin and noradrenaline reuptake. Hypertension is observed in doses exceeding 300 mg/day and is the most feared complication. We report a patient with accelerated hypertension after Valosine use observed at a dose of 150 mg/day. A 23-year-old patient with symptoms of insomnia, depression, anhedonia, fatigue admitted our clinic. Valosine at a dose of 75 mg/day was initiated after he was diagnosed with major depressive disorder. After 5 months, Valosine dose was uptitrated to 150 mg/day due to inadequate response to drug. After using Valosine for ten months at the dose of 150 mg/day, he admitted our clinic with headache and epistaxis. He was hospitalized after his blood pressure was measured as 210/170 mmHg. No secondary causes for hypertension were found, and Valosine treatment was considered possible etiologic factor. After stopping Valosine treatment, his blood pressure was reverted back to normal limits. While mild elevation of blood pressure could be observed after Valosine treatment, this case shows that accelerated hypertension with a diastolic blood pressure rise above 120 mmHg could be observed at relatively low doses of Valosine. Close monitoring of blood pressure is necessary after initiation of treatment, as accelerated hypertension could cause endorgan damage with potentially catastrophic results.
Other names for this medication:
Venlafaxine,
Alventa,
Argofan,
Benolaxe,
Dobupal,
Efectin,
Efexor,
Effexor,
Elafax,
Faxine,
Flavix,
Melocin,
Memomax,
Mezine,
Nervix,
Norpilen,
Senexon,
Sesaren,
Subelan,
Tavex,
Tifaxin,
Trevilor,
Valax,
Valosine,
Vandral,
Velafax,
Velaxin,
Venax,
Venex,
Veniz,
Venla,
Venlafaxina,
Venlalic,
Venlax,
Venlaxor,
Venlift,
Vensir,
Viepax,
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Benefits of antimuscarinic therapy may be greater in these patients than previously reported. Plasma, urine, proximal 1 cm of hair and distal hair were each analyzed for codeine and its metabolites by positive-ion fexofenadine hydrochloride 180 mg film coated tablets crushed chemical ionization ion trap gas chromatography/mass spectrometry.
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The influence of moisture wound healing on the incidence of bacterial infection and histological changes in healthy human skin after treatment of interactive dressings. Polyomaviruses of birds: etiologic agents of inflammatory diseases in a aktil duo 500 mg filmtabletta tumor virus family. Tunneling and quantum noise in one-dimensional Luttinger liquids. Thus, it can be noted that EC is very well-suited for the simulation of the oxidative metabolism of verapamil.
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To clarify the allergenicity of booklice and the cross-reactivity of this insect allergen with allergens of other insects, patients sensitized to booklice were identified from 185 Japanese adults with allergic asthma using skin tests and IgE-ELISA. MCDK has an incidence of 1: 4300 escitalopram alcohol interaction of live births and is usually unilateral, most commonly occurring in the left kidney.
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