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Zanaflex (Tizanidine)

Zanaflex is a prescription drug that comes as an oral tablet and an oral capsule. Zanaflex oral tablet is available as a brand-name drug Zanaflex. It’s also available as a generic drug. Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in all strengths or forms as the brand-name drug. Zanaflex oral tablet is used to manage muscle spasms. Symptoms can include muscle tightness, pain, or stiffness. This drug is often used for people with multiple sclerosis, spinal cord injury, or muscle spasticity. Zanaflex belongs to a class of drugs called alpha-2-adrenergic agonists. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions. Zanaflex reduces the activity of nerves in the spinal cord that control muscles. This helps to reduce muscle spasms.

Other names for this medication:
Tizanidine, Zanaflex, Ternelin, Tizan, Tizanidina,

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A case of neonatal ascites due to malformation of the urinary tract Embryos were exposed to different MYS concentrations from stage 8 to stage 47. Bone tumor induction after incorporation of short-lived radionuclides.

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Child maltreatment is a serious problem in US society, affecting approximately three million children. This was due to the inactivation of cefotaxime by extracellular cephalosporinase which was induced by cefmetazole and which remained in the rat pouches. Effects of different dose schedules of amethopterin on serum and tissue concentrations and urinary excretion patterns. The mitotic and apoptotic indices and Ki67 expression increased significantly in parallel with the severity of dysplasia and also with the clinical stage (homogenous, nodular, erythroleukoplakia). Edmond decourtive and the first thesis on hashish: a historical note and translation.

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Remedial parathyroid surgery can be accomplished with acceptable cure and complication rates. Apoptosis and cytologic differentiation in hepatocellular carcinoma on fine needle aspiration samples. JIY experience more and longer gaps in Medicaid coverage, and rely more on emergency services than NJIY. Pseudomonas aeruginosa PA1006 is a persulfide-modified protein that is critical for molybdenum homeostasis.

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Luminol-dependent chemiluminescence of hemocytes derived from marine and estuarine molluscs. In this study, we show by confocal microscopy that FasL and APO2L/TRAIL are mainly localized in lysosomal-like compartments in these cells. These data suggest that increased bone mass maintenance, known to occur in heavier individuals, is not accompanied by increases in the lamellar-level elastic modulus or hardness. However, in the lungs of SCID mice, bacillus Calmette-Guerin was regionally distributed mostly in isolated alveolar macrophages and in aggregates of macrophages resembling small granulomas.

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Formaldehyde adsorbed on passive air samplers was quantified by HPLC with UV detection (360 nm), cotinine was quantified by GC-MS. Supporting those responsible for the health care for children in the developing world: CHILD2015. These results increase our knowledge of the ontogenesis of dystrophin and may lead to a better understanding of the great diversity in pathological cases of Duchenne and Becker muscular dystrophy. Thus, the stress response appears to be useful to monitor the sublethal toxicity resulting from a single exposure to arsenite.

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Variants and congenital anomalies of the coronary arteries are usually asymptomatic, but may present with severe chest pain or cardiac arrest. PCR-detectable nonneoplastic Bcl-2/IgH rearrangements are common in normal subjects and cancer patients at diagnosis but rare in subjects treated with chemotherapy. The elderly who live alone in the United States: historical perspectives on household change.

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Mice lacking CD2AP die soon after birth because of kidney failure. This paper sets out the rationale, objectives and mission for the UK-SEA-ME Psychosocial-Cultural Cancer Research Network. Antagonists of CD117 (cKit) signaling inhibit mast cell accumulation in healing skin wounds.

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Anger and Afrophobia in South Africa: What is a health practitioner to do? Th1-driven IL-12 production depends on TCR ligation by MHC class II/peptide complexes, CD40 engagement on microglia, and IFN-gamma secretion by activated Th1 cells. We have therefore identified a novel lymphoid nuclear protein induced by T cell activation that occurs in tat-I expressing cells in the absence of activating agents. In addition, induction of MAPK phosphorylation was found to be independent of PAR1 activation.

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These results show that the NLRP3 inflammasome impairs host defense during lethal pneumonia caused by serotype 3 S. This model, developed primarily on the basis of x-ray diffraction results, is necessarily vague about the cross-sectional organization of fibrils and has led to the widespread assumption of laterally homogeneous closepacking. Induction of protein kinase PKR-dependent activation of interferon regulatory factor 3 by vaccinia virus occurs through adapter IPS-1 signaling.

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Chronic pain following breast cancer surgery is associated with decreased health-related quality of life and is a source of additional psychosocial distress in women who are already confronting the multiple stresses of cancer. The presence of surfactant at the lipid/water interface of the SLN seems to be mandatory to allow the adsorption of the lipase and degradation of glyceryl behenate.

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Regulation of immunity within the immune-privileged ocular microenvironment is a dynamic interaction of anatomical features, factors, and cells that work toward suppressing the induction inflammation. Work is continuing to accumulate a significant body of evidence to evaluate results of these changes in technique and to develop optimal IOL designs and selection criteria for these specialized cataract patients.

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Most pituitary cells show morphologic changes that reflect stimulation or inhibition by hormones. Reduced sensitivity to beta-adrenergic agonists in Basenji-Greyhound dogs.

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The patients, ranging in age from 15 months to 9 years, had cerebral infarctions documented by computed axial tomography scan or magnetic resonance imaging associated with the echocardiographic finding of thrombus in the proximal pulmonary artery stump after the embolic strokes. Intensive preoperative nutritional support should be used only in malnourished patients undergoing major surgical procedures and in patients receiving preoperative radio- and/or chemotherapy, irrespective of nutritional status. However, the infectivity of neutralized IBDV by MN-Ab was confirmed on CSA cells which were blocked for FcR on CSA cells by heat-aggregated NCS (56 degrees C, 60 min). In vitro and in vivo correlates of antiidiotypic immunization in inbred strains of rats. In addition, bio-distribution of MN-OA in tumour/other target organs and its effect on normal organ function were studied by Prussian blue staining and serum biochemical analysis, respectively.

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The parafollicular cells of male and female rats neonatally (3rd day) treated with a single dose (1 mg) of estradiol dipropionate, and sacrificed in peripubertal (38th day) or adult (80th day) period of life, were investigated. This successful pilot encouraged our school to migrate the curriculum of a traditional RN to BS program to an online format. In the parietal bones a gradual increase in both values was observed until they reached a plateau at the age of 30 weeks. These include use of the naturally occurring anti-oxidants in human plasma, specifically transferrin and ceruloplasmin. Lowering BP, even several years posttransplantation, was associated with improved graft and patient survival in renal transplant recipients.

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To evaluate the safety and physiologic actions of ibuprofen in patients with severe sepsis. A Concept Design of Flat-Field Spectrograph for Wide Wavelength Range The N-DRC forms a conserved biochemical complex that maintains outer doublet alignment and limits microtubule sliding in motile axonemes. DMSO- and HMBA-differentiated FEL cells showed changes in alkenyl- and alkyl-chain profiles, some of which were also observed in non-inducible FEL cells treated with DMSO or HMBA.

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Glycogen synthase kinase-3 regulation of chromatin segregation and cytokinesis in mouse preimplantation embryos. The microbiology and management of acute dentoalveolar abscess: views of British oral and maxillofacial surgeons. MRI was accomplished in 5 patients presenting temporal lesion in 3 and temporo-parietal in 2. Patients were pair matched for age, PSA level, clinical stage, preoperative biopsy Gleason score and bone metastases.

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Induced segregation in interspecific hybrids of Aspergillus nidulans and Aspergillus rugulosus obtained by protoplast fusion. The physiological or pathological signification of its variation has to be deduced from clinical evaluation.

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The role of polyunsaturated fatty acids, especially linoleate, in the enhancement of resistance to bacterial infection Thus, the instability of thick filaments seen in vivo in the absence of flightin suggests that the flightin myosin interaction is critical for maintaining sarcomere integrity in active muscle. The transfected cells adapted to the injured muscle, formed myofibers positive for dystrophin and negative for MyoD and myogenin. Pneumomediastinum, pneumorachis, subcutaneous emphysema: An unusual complication of leukemia in a child. Secretion of catecholamines, ascorbic acid, progesterone and corticosterone by in-vitro superfusion from the adrenal of the Mongolian gerbil (Meriones Unguiculatus): effects of confinement stress.

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Naturoceutical agents in the management of cardiovascular disease. Here, we used RNA interference to ablate IE1, plus its splice variant IE0, and thereby define in vivo activities of these early proteins, including gene-specific regulation and induction of host cell apoptosis. MMP-2 and MMP-9 are associated with increased risk of recurrence and decreased survival in patients with colorectal cancer. We modified our isolation protocols by increasing the duration of detergent Triton X-100 treatment for preparing the PSI and LHCII complexes from 27-day cotyledons.

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Hypercapnic acidosis reduced the magnitude of the lung injury induced by established E. In this article, the literature examining the relationship between testosterone and various cognitive domains in elderly men is reviewed. Hepatocyte apoptosis was determined by terminal dUTP nick-end labeling. Older patients with multiple chronic conditions may be at higher risk of receiving poorer overall quality of care compared with those with single or no chronic conditions.

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Results of randomized controlled trials (RCTs) provide high-level evidence for evidence-based practice (EBP). A colour test to distinguish between the fruits of Illicium verum and Illicium anisatum L.

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Guinea-pigs infected with Angiostrongylus cantonensis developed pleocytosis and eosinophilia in the cerebrospinal fluid (CSF) at day 12 post-infection (p.i.), showing a peak response at day 20 p.i., followed by a gradual reduction. Subjects with the lowest percentage of predicted expiratory volumes and flows demonstrated the greatest improvement when electrical stimulation was delivered during forced expiration. Moreover, leukocyte adhesion to NG2 siRNA-treated pericytes was significantly enhanced when compared to scrambled (scr) siRNA-treated control cells. Hodgkin disease developing in patients infected by human immunodeficiency virus results in clinical features and a prognosis similar to those in patients with human immunodeficiency virus-related non-Hodgkin lymphoma. Limited evidence of a relation between an unhealthy dietary pattern and risk of upper aerodigestive tract, pancreatic, ovarian, endometrial, and prostatic cancers relied only on case-control studies.

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The findings suggest that minimally oxidized LDL may be a local mediator promoting thrombosis in atherosclerotic lesions. In this paper, an expression of the magnetic diagnostic response to the coil currents is used to calibrate the mutual inductances, estimate the conductor time constant, and predict the eddy currents response. An 87-year-old woman who had undergone a DSAEK 4 months previously was referred to Tokushima University Hospital with a diagnosis of infectious keratitis after DSAEK. Fractals were observed for the brush copolymer aqueous solution in the presence of NaCl.

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To compare dogs with glucocorticoid-deficient hypoadrenocorticism (GDH) with those with mineralocorticoid- and glucocorticoid-deficient hypoadrenocorticism (MGDH) and determine prevalence, historical and clinicopathologic markers, and outcome of dogs with GDH. The total ovarian content of NKA was not significantly different in the three groups of animals studied. Receptive field (RF) dimensions were measured using drifting gratings and bipartite field stimuli. Effects of diet-induced moderate weight reduction on intrahepatic and intramyocellular triglycerides and glucose metabolism in obese subjects.

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Given the unique nature of assisted living facility (ALF) settings, the present study made a distinction between social engagement within and outside the facility and explored how these two types of social engagement would interact with functional disability in predicting depressive symptoms of older residents in ALFs. The yield of neurospheres from limited dilution or single cell cultures is very low so the authors studied cells generated per 10(5) viable cells from a cell suspension derived from whole retina. Furthermore, KN93 also significantly prohibited HCT116 cell migration and invasion. A critical appraisal of the published literature reveals that there is little actual experimental or clinical evidence favouring the role of catecholamines in the pathogenesis of hypertrophic cardiomyopathy. Uncommon invasive fungal pathogens in the acquired immunodeficiency syndrome.

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Role of antidiuretic hormone and hyaluronidase in the mechanism of the concentration of urine. The authors developed a method to quantify the degree of tendon torsion, explore a possible relationship to external anatomical landmarks, and suggest that the development of tendoachilles torsion closely follows postnatal development of the tibia. The concentrations and distribution of the nanoparticles with respect to size were also measured directly using a differential mobility analyzer and ultrafine condensation particle counter.

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Therapy of verrucae by means of administration of methyl-methonine-sulfonium chloride (Epadyn U) Two-Dimensional Capillary Electrophoresis with On-Line Sample Preparation and Cyclodextrin Separation Environment for Direct Determination of Serotonin in Human Urine. Frozen 8-cell mouse embryos were treated with radiation doses of 0, 10, 50, 100 or 200 cGy gamma-rays at a dose rate of congruent to 5 cGy/day. Mouse endothelial cells showed a similar HDL uptake pattern in vivo indicating that the endothelium is one major site of HDL endocytosis and transcytosis. Drug efficacy, toxicity, patient adherence, treatment interruption and the importance of generic drugs in resource-poor settings were also extensively discussed.

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After modification of the ventilation system and implementation of improved cleaning methods in the operating theater, no new cases were recorded. Genetic deletion of ILK suppresses ErbB2-driven YAP/TAZ activation in mammary tumours, and its pharmacological inhibition suppresses YAP activation and tumour growth in vivo. The objective of this review was to evaluate how elements of the 7 steps of implementation, developed by Padua et al, have been performed in the evidence of lower extremity preventive training programs. We reviewed the database of patients enrolled in the Compassionate Use Registry between August 1999 and July 2000. Morphological changes and depressed phagocytic efficiency in Dictyostelium amoebae treated with toxic concentrations of cadmium.

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We further show that the Fe-S domain is essential to the unique ability of the eukaryotic primase to start DNA replication. Additionally, a large number of sperm in the epididymal lumen exhibited abnormalities including malformation of head and tail components. Methylmercury has been shown to inhibit the primary, secondary and memory immune response but few studies have described possible effects on T lymphocytes and macrophages.

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Among HIV/SIV coreceptors we tested, the expression of GPR1 mRNA was detected in mesangial cells. In the over 60 age group water transport episodes remained the most frequent, with swimming pool related episodes declining and other specified drowning and submersion increasing. The idea has been changing with regards to the extracranial venous system. microplus ticks fed on cattle have overrepresented tick proteins involved in blood digestion and reproduction when compared to ticks fed on WTD, while host proteins were differentially represented in ticks fed on cattle or WTD.

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This article describes some of the recent advances in cophylogenetic simulation, significance testing, and theoretical properties of maps. Evidence suggests that many consumers possess limited levels of health literacy to adequately understand health information, especially when they are feeling ill, since health literacy is both a trait (limited education, language facility, etc.), and a state condition (based on how their current physical and mental states influence their abilities to communicate effectively).

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The malignant phenotype of breast cancer cells is reduced by COX-2 silencing. The recruitment and engagement of breast cancer survivors in a 2-year community development project that used participatory, women-driven approaches are discussed, and the reciprocal learning between health care providers, community partners, and women living on low income is shared.

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Although many Canadian resident physicians have a positive outlook on their well-being, residents experience significant stressors during their training and a significant portion are at risk for emotional and mental health problems. In the eyestalk, Csp is associated with cells surrounding axons between neuropils of the eyestalk ganglia. It can detect the occlusive sites in the main arteries, especially the middle cerebral artery, and as of benefit for anticipation of the ensuing edematous area. The continuing multidisciplinary needs of adult patients with cleft lip and/or palate. Preparation was accomplished via simple synthetic protocols affording free flowing powders, amenable for large-scale production.

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ERG25, an enzyme involved in cholesterol biosynthesis, is expressed in vascular endothelial and SMC from porcine and human origin and is downregulated by LDL in a time- and dose-dependent manner. These guidelines are preliminary in nature and intended to provide a starting point for discussion among physicians, nurses, and mental health professionals regarding the psychological needs of infertility patients. These results suggest that these algae grown in standard culture media are generally no more sensitive than algae grown in a metal-enriched medium.

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In addition to infecting host NIH 3T3 cells, some of pseudotyped viruses could transduce human cells. Platelet adhesion and aggregation at sites of vascular injury are critically dependent on the interaction between von Willebrand factor (VWF) and 2 major platelet adhesion receptors, glycoprotein (GP) Ib/V/IX and integrin alpha(IIb)beta(3). The serum alkaline phosphatase is increased, too, whereas the values for the transaminases and gamma GT are normal or only slightly elevated. 1978 Survey of educational programs in speech-language pathology and audiology. The pars plana approach in two cases of persistent hyperplastic primary vitreous (PHPV).

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To determine the risk of recurrent stress urinary incontinence in women undergoing the combined modified Pereyra procedure and sacrospinous ligament vault suspension. We observed that the immunosuppressed mice, treated with the whole extract of the bitter yellow juice achieved restoration of immunological parameters in cellular immune response and phagocytosis.

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However, an asymptomatic type III endoleak due to controlateral limb disconnection was detected at the followed schedulated CT angio and corrected by a relining of the endograft. For each disease, the sampling frame was the district, but for schistosomiasis, the sub-district rather than the ecological zone was used. We constructed a computer simulation model of the natural history of colorectal neoplasia.

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The greater tuberosity notch seems to be one of the most important diagnostic indicators for a rotator cuff tear in throwing athletes. This association between polymorphisms from genes related to estrogen metabolism and prostate cancer risk suggest new clinical considerations in the management of prostate cancer: the development of new prevention trials based on genetic profiling and the evaluation of specific inhibitors involving the estrogen pathways. The amplitiude of evoked responses of occipital cortex in man depends on the visual field in which the stimulus appears. In non-irradiated mice the PCST-increasing effect of CP occurs rapidly (5 min) and it is brief (it can be observed until the 15th min). Spatiotemporal analysis of prepyriform, visual, auditory, and somesthetic surface EEGs in trained rabbits.

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The aim of this prospective longitudinal study was to analyze and report the practice of CNS prophylaxis and treatment in patients with AL in Spain. However, PEPCK enzyme showed continuous hyperactivity for over 72 h. Metabolic syndrome (MS) may lead to worsened left ventricular systolic function by causing recurrent thrombotic events and by aggravating systemic inflammation in the course of acute myocardial infarction.

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The results support the conclusion that juvenile animal tissue, exhibiting a highly complex collagenous architecture, may not always serve as a realistic model for mature human tissue with a typical three-zone network organization, and other than bulk metrics are required for the analysis of cartilage T(2). Continuous-Wave Operation of a 460-GHz Second Harmonic Gyrotron Oscillator. Skin prick tests with nabumetone (10 and 100 mg/mL) were negative. Demographic Characteristics of Type 1 Diabetic Children and Adolescents in Hamadan, Iran.

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Structured assessment of independent living skills: preliminary report of a performance measure of functional abilities in dementia. Gypenosides Reduced the Risk of Overweight and Insulin Resistance in C57BL/6J Mice through Modulating Adipose Thermogenesis and Gut Microbiota. Nitric oxide is an essential mediator for the transfer from short- to long-term memory. The success of DBS and other forms of neuromodulation for neuropsychiatric disorders is the result of the ability to modulate circuit activity in discrete acyclovir dosage in herpes encephalitis symptoms functional domains within the basal ganglia circuitry with highly focused interventions, which spare uninvolved areas that are often disrupted with drugs.

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coli Nissle 1917 DeltafucAO mutant, derived from a human probiotic commensal strain, acted in a manner identical to that of E. Endogenous omeprazole actavis 20 mg bijsluiter medrol expression of E1A in human cells enhances the effect of adenovirus E3 on class I major histocompatibility complex antigen expression.

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Clinical Potential of Statins in Prostate Cancer Radiation Therapy. The Protein Information Resource: lansoprazole drug description on prescription an integrated public resource of functional annotation of proteins. This review explores the physiological functions and molecular actions of bioactive lipids biosynthesized in adipose tissue including sphingolipids and phospholipids, and in particular fatty acids derived from phospholipids of the cell membrane. The aim is to present the phacoemulsification phaco-chop technique in a patient with pseudoexfoliation (PEX) syndrome without the use of additional pupil dilatation methods. Hyaluronic acid based self-assembling nanosystems for CD44 target mediated siRNA delivery to solid tumors.

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Mammalian development to adulthood typically requires both maternal and paternal genomes, because genomic imprinting places stringent limitations on mammalian development, strictly precluding parthenogenesis. Regenerative medicine and in vivo biosensor applications require the formation of mature vascular networks for long-term success. Primary renal epithelioid angiosarcoma enoyl acyl carrier protein reductase-5 with transitional cell carcinoma in renal pelvis We provide experimental data consistent with the latter hypothesis. This evidence suggests that perseverative and non-perseverative errors result from disruptions in two different prefrontal neural networks engaged during card sorting.

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This data set provides the information required to better evaluate computational ticagrelor vs clopidogrel pharmacokinetics of aspirin models of the thorax for side impact simulations. Scanning-tunneling-microscope study of the alpha and beta phases of the GaAs (001)-(2 x 4) reconstruction.

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